Hubungan Laju Endap Darah dengan Skor Depresi dan Palliative Prognostic Index pada Pasien Kanker Paliatif

Abstract

Background:Patients with advanced-stage cancer face various physical and psychological complications. Depression, which frequently occurs in palliative cancer patients, contributes to poor quality of life and increased mortality. The relationship between Erythrocyte Sedimentation Rate (ESR) as an inflammatory marker and depression scores and the Palliative Prognostic Index (PPI) is not fully understood. This study aims to determine the relationship between ESR, depression scores, and PPI in palliative cancer patients. Methods: This analytical observational study utilized a retrospective approach using medical records of palliative cancer inpatients at Adam Malik Hospital, Medan, from June to August 2024. Eligible subjects underwent blood tests to assess ESR, depression scores using the Beck Depression Inventory II (BD-II), and PPI. The Kruskal-Wallis test was used to compare ESR with depression scores and PPI. A p-value of <0.05 was considered statistically significant. Results: A total of 103 subjects were included, with an average age of 45 years; 74 were women (71.8%) and 29 were men (28.2%). Ages ranged from 18 to 78 years. Statistical analysis revealed significant relationships between ESR and depression scores (p = 0.001) and ESR and PPI (p = 0.007) in palliative cancer patients. Conclusion: ESR can serve as an additional indicator for predicting depression and PPI scores in palliative cancer patients.