Hubungan Gambaran Nilai Awal Laju Filtrasi Glomerulus dengan Ketahanan Hidup Pasien Penyakit Ginjal Kronik Stadium V yang Menjalani Hemodialisis Reguler

Abstract

Background. Chronic Kidney Disease (CKD) has become one of the most common causes of death worldwide. The mortality rate in CKD patients undergoing hemodialysis increased by 0.6% in 2021. Objective. To determine the relationship between the initial Glomerular Filtration Rate (eGFR) value and the survival of stage V CKD patients undergoing regular hemodialysis. Methods. This study is an analytical study with a cross-sectional design conducted from July to September 2024 at Prof. Dr. Chairuddin, P. Lubis Hospital, Medan. The inclusion criteria for the study sample were stage V CKD patients recorded in the medical record starting regular hemodialysis in 2021-2023 and the exclusion criteria for the study sample were patients with incomplete medical record data. Data were analyzed using Kaplan Meier survival curve and the log-rank test. Results and Discussion. Of the 65 research samples, the largest distribution was the 45-59 year age group (40%), male (64.6%), starting hemodialysis with an initial eGFR value of <5.0 ml/minute/1.73 m2 (44.6%), and undergoing regular hemodialysis for <12 months (56.9%). The average initial eGFR value was 5.74 ml/minute/1.73 m2. The log-rank test results did not obtain a significant value (p-value >0.05). Conclusion. There is no significant difference in survival based on the initial eGFR value at the time of hemodialysis initiation.