Hubungan Antara Usia Gestasi dan Berat Badan Lahir dengan Kadar Bilirubin pada Neonatus di RS Mitra Medika Premiere dan RS Prof. Dr. Chairuddin P. Lubis Universitas Sumatera Utara pada Tahun 2022-2024
The Relationship Between Gestational Age and Birth Weight with Bilirubin Levels in Neonates at Mitra Medika Premiere Hospital and Prof.Dr. Chairuddin P. Lubis Universitas Sumatera Utara Hospital 2022-2024
Abstract
Background. Neonatal hyperbilirubinemia is a significant challenge in newborn
care, particularly in preterm or low birth weight (LBW) infants who are at higher
risk. Studies in Nepal and Indonesia indicate an increased incidence of
hyperbilirubinemia, potentially leading to neurological complications such as
kernicterus. This study explores the relationship between gestational age and
LBW with bilirubin levels and compares the incidence of hyperbilirubinemia
between hospitals to support more effective prevention strategies. Subject and
Methods. This study employed an observational analytic design with a crosssectional
approach. A total of 60 neonates (0–28 days old) treated at Mitra
Medika Premiere Hospital and Prof. Dr. Chairuddin P. Lubis Hospital from
2022–2024 were selected using consecutive sampling. Data were analyzed using
the chi-square test. Results. Most neonates at Mitra Medika Hospital were male
with normal gestational age (66.7%), whereas at Prof. Dr. Chairuddin P. Lubis
Hospital, the majority were female with preterm gestational age (56.7%).
Gestational age and LBW were significantly associated with the incidence of
hyperbilirubinemia (p<0.05) in both hospitals. A total of 33% of neonates at
Mitra Medika and 35% at Prof. Dr. Chairuddin P. Lubis experienced
hyperbilirubinemia, with no significant difference between hospitals (p>0.05).
Conclusion. Gestational age and LBW are significantly associated with
hyperbilirubinemia in neonates. Preterm and LBW infants are more prone to
severe and prolonged hyperbilirubinemia, increasing the risk of neurological
complications. Equal access to healthcare services and early detection are
essential for preventing complications in both hospitals.
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