Hubungan Tingkat Pengetahuan Ibu Terkait Infeksi dan Pencegahan Cytomegalovirus Kongenital (CCMV) dengan Status Infeksi Cytomegalovirus (CMV) pada Bayi Baru Lahir di RS Prof. Dr. Chairuddin Panusunan Lubis USU Medan

Abstract

Introduction. Cytomegalovirus is a part of TORCH infections during pregnancy and is the leading cause of congenital infections worldwide. Vertical transmission during pregnancy could occur and this could result in the birth of neonate with congenital cytomegalovirus (cCMV). Infection status of the said neonates can be done either serologically or done with polymerase chain reaction (PCR) of urine sample. The outcomes of this infection vary from neurological defect to sensorineural hearing loss. In Indonesia, number of studies and data related to congenital cytomegalovirus is insufficient to determine the prevalence of this infection. Objective. This study aims to determine the association between maternal knowledge, attitude, and behavior towards congenital cytomegalovirus infection and prevention in Prof. dr. Chairuddin Panusunan Lubis USU Hospital. Method. Cross-sectional study is done in 35 neonates admitted to Prof. dr. Chairuddin Panusunan Lubis USU Hospital. Maternal demographic data, knowledge, attitude, and behavior are acquired through questionnaires, while the neonates’ demographic data and clinical characteristics are acquired through medical records and infection status of the neonates are determined through a nested PCR with urine sample and visualized with gel electrophoresis. Results and Discussion. 77,1% of mothers show a low level of knowledge; however, 82,9% of mothers show a positive attitude towards the knowledge of cytomegalovirus infection and prevention. As much as 34,3% of mothers very frequently engage in behaviors that increase the risk of cytomegalovirus transmission; even so, 51,4% of the said mothers also very frequently engage in behaviors that prevents cytomegalovirus transmission. Conclusion. The incidence of congenital cytomegalovirus in Prof. dr. Chairuddin Panusunan Lubis USU Hospital is 20,0%.