Analisis Penggunaan Insulin Dibandingkan Kombinasi Oral Anti Diabetikum terhadap Kejadian Neuropati Diabetikum pada Pasien Lanjut Usia Diabetes Melitus Tipe 2 di Rumah Sakit Pendidikan Prof Dr Chairuddin Panusunan Lubis

Abstract

Diabetic neuropathy is one of the most common complications in patients with type 2 diabetes mellitus (DM), particularly in elderly patients. Insulin and the combination of oral antidiabetics (OAD) are the primary therapeutic options for type 2 DM, which can improve blood glucose levels and potentially prevent complications such as diabetic neuropathy. This study aimed to compare the incidence of diabetic neuropathy in elderly patients treated with insulin versus a combination of oral antidiabetics at Prof. dr. Chairuddin Panusunan Lubis Hospital, Medan. This research employed a cross-sectional study design involving 58 patients who met the inclusion criteria. Data analysis was conducted using the Chi-Square test to assess the relationship between the type of therapy and the incidence of diabetic neuropathy. The results showed a significant difference in the incidence of diabetic neuropathy between patients treated with insulin and those treated with a combination of OAD (p = 0.021). There is a significant difference between the use of insulin and the combination of oral antidiabetic drugs in the incidence of diabetic neuropathy among elderly patients at Prof. dr. Chairuddin Panusunan Lubis Teaching Hospital.