| dc.description.abstract | Background: Body Mass Index (BMI) is an indicator of obesity, and another
parameter that can assist in diagnosing obesity is waist circumference. In 2022,
approximately 16% of adults over 18 years of age worldwide experienced obesity.
Leukocyte levels are markers of inflammation, where white blood cells, including
neutrophils, lymphocytes, monocytes, eosinophils, and basophils, are key components
of the immune system involved in the inflammatory response. Leukocytes positively
correlate with BMI, and an increase in BMI has been proven to be a strong predictor
of future diabetes mellitus (DM) onset across various populations. Objective: To
determine the correlation between leukocyte levels, leukocyte profile, and platelet
count with nutritional status among students of the University of North Sumatra.
Subjects and Methods: This study employed a cross-sectional design using data
obtained from the University of North Sumatra Clinic. The independent variable in this
research was BMI, while the dependent variables included leukocyte levels, leukocyte
profiles (including lymphocytes, mixed basophils/eosinophils, and neutrophils), and
platelet count. The analytical methods used were Spearman Rank correlation test and
logistic regression. Results: The study results showed a significant relationship
between leukocyte levels (P = 0.0001) and platelet count (P = 0.0001) with nutritional
status. However, the leukocyte profile did not show a meaningful correlation with
nutritional status. Lymphocytes had a correlation value of 0.123, mixed
basophils/eosinophils/monocyte 0.462, and neutrophils 0.112, which may be due to
external factors not covered in this study. Conclusion: It can be concluded that
leukocyte and platelet levels correlate with nutritional status, while the leukocyte
profile showed a weak association with nutritional status. | en_US |
