Perbandingan Efek Antidiabetes Ekstrak Etanol Bawang Hitam (Allium sativum L. Varietas Kating) dengan Bawang Hitam Tunggal (Allium sativum L. Varietas Solo Garlic) pada Mencit (Mus muscullus) yang Diinduksi Aloksan

Abstract

Background: Black garlic is an alternative used by the public to treat diabetes. Previous research conducted on single black garlic using UV-Vis spectrophotometry and on compound garlic in vivo at a dose of 300 mg/kgBB showed activity in reducing blood glucose levels. In this case, no one has carried out a comparison between single black onions and compound black onions in vivo. Objective: To see whether single black garlic and kating black garlic can reduce blood glucose levels in mice and to see whether there is a significant difference in the activity of reducing blood glucose levels in mice based on statistical results. Method: This study used an experimental method with research stages, testing the activity of the antidiabetic effect on reducing blood glucose levels (KGD) in mice using the alloxan-induced method. Data were analyzed using the SPSS (Statistical Product and Service Solution) program. Results: The single black garlic ethanol extract (EEBHT) and kating black garlic ethanol extract (EEBHK) groups could reduce blood glucose levels (KGD) in mice at a dose of 150 mg/kgBB. The EEBHT and EEBHK treatments showed that there was no significant difference in the reduction in blood glucose levels that occurred in mice, indicated by the sig value. > 0.05. Conclusion: EEBHT and EEBHK can reduce KGD in mice and there is no significant difference in antidiabetic activity in both samples