| dc.description.abstract | Introduction Sweet arum mango leaves (Mangifera indica L.) are one of the
potential natural ingredients as an antifungal because it has bioactive components like
mangiferins, flavonoids, tannins, and saponins. The overall role of sweet arum mango
leaf phytochemicals can suppress the growth of fungi from within the cell, thereby
damaging membrane permeability, causing fungal lysis. Candida albicans is a normal
flora microorganism in the oral cavity that can turn into a pathogen if there is a
change in the oral environment. Treatment is carried out with alternative herbs,
namely sweet arum mango leaf extract against Candida albicans from angular
cheilitis patients.. Purpose of the study was determine the inhibitory power,
inhibitory power differences, minimum inhibitory concentration (MIC) and minimum
bactericidal concentration (MBC) of sweet arum mango leaf extract and Candida
albicans colony forming units after giving the sweet arum mango leaf extract.
Method is experimental laboratory post test only control group design. Inhibition
testing using blank disk diffusion method with digital calipers, determination MIC
and MBC dilution method. Preparation of extract by maceration method from each
concentration added to fungal suspension, 4 repetitions and then observations were
made. Parametric analysis using Oneway Anova Test and Post-hoc LSD test with a
significance value of p<0.05, if the data obtained is not normally distributed and
homogeneous, non parametric analysis with Kruskal-Wallis test and Mann Whitney
test. The result of the study of the inhibition of sweet arum mango leaf extract
concentrations of 5%, 10%, 15%, 20% and 25% diameter 9,38 ± 0.433 mm, 10.63 ±
0.479 mm, 14.00 ± 1.061 mm, 18.69 ± 0.851 mm dan 21.188 ± 0.625. The
effectiveness of sweet arum mango leaf extract of several concentrations against
Candida albicans is MCI 5% and MBC 25% Conclusion sweet arum mango leaf
extract effective against Candida albicans. | en_US |
