Waktu Optimal Operasi Kraniotomi Dekompresi pada Pasien Trauma Kepala terhadap Luaran Klinis: Studi Meta-Analisis

Abstract

Introduction: Traumatic Brain Injury (TBI) is a major health issue, often leading to death or long-term disability. Decompressive craniectomy (DC) is a surgical procedure used to reduce intracranial pressure (ICP) in severe cases, but the best timing for this surgery remains unclear. Methods: This study is a meta-analysis following PRISMA guidelines. Research was collected from seven databases, focusing on studies comparing early (<24 hours) and late (>24 hours) DC. Data on patient characteristics, CT scan results, treatment timing, and outcomes were analyzed. Results: Out of 2,571 studies, 23 met the inclusion criteria. The analysis showed that early DC significantly reduces ICP and improves survival rates (p=0.0003). However, some studies reported higher mortality and complications with early surgery. Discussion: While early DC generally improves survival, its impact on long-term recovery is uncertain. Differences in study methods and patient conditions make it difficult to determine the best approach. More high-quality research is needed to confirm these findings. Conclusion: Early DC may help save lives in severe TBI cases, but its effect on recovery remains unclear. Further studies are needed to determine the best timing for this procedure.