Uji Efektivitas Antibakteri Ekstrak Daun Pala (Myristica fragrans Houtt) dalam Menghambat Pertumbuhan Streptococcus mutans secara In Vitro

Abstract

A problem that is currently occurring in developed and developing countries regarding dental and oral health is dental caries. One of the countries where dental caries is often found is our own country, namely Indonesia.1 Behavioral factors that ignore the cleanliness and health of the teeth and mouth are one of the factors causing problems with the teeth and mouth. This is due to a lack of knowledge about the health and maintenance of teeth and mouth. The World Health Organization (WHO) has recommended the use of traditional medicines, such as plants and herbal plants to maintain public health. One of these medicinal plants is nutmeg. This study used 7 treatment groups, namely; group 1: Nutmeg leaf extract 50%, Group 2: Nutmeg leaf extract (25%, group 3: Nutmeg leaf extract 12.5%, group 4: Nutmeg leaf extract 6.25%, group 5: Nutmeg leaf extract 3.125%, group 6: Dimethyl sulfoxide (Negative Control), group 7: Chlorhexidine gluconate 0.2% (Positive Control). Kirby-Baeur, where sterile paper discs were soaked in nutmeg leaf extract and left for 24 hours and the inhibition zone was calculated, then the most effective results were obtained in group 1 with 50% nutmeg leaf extract with an inhibition zone of 16,525 mm.