Perbandingan Penggunaan Haloperidol Intravena dan Ondansetron Intravena Pada Intraoperatif Terhadap Penurunan Angka Kejadian Post Operative Nausea Vomiting (PONV) Pada Pasien Regional Anestesi Sub Arachnoid Blok (RASAB)

Abstract

Background: Postoperative Nausea and Vomiting (PONV) is a common complication that disrupts patient recovery and increases healthcare costs. Effective management is crucial. This study compares the effectiveness of intravenous haloperidol and ondansetron in reducing PONV in patients undergoing Sub Arachnoid Block (SA-B) anesthesia. Methods: A true experimental study using a double-blind randomized prospective cohort method was conducted at RSUP H. Adam Malik Medan and Rumah Sakit Umum Haji Medan to compare the effects of intravenous haloperidol and ondansetron on PONV in RA-SAB patients. Results: The average age in the haloperidol group was 34.9 ± 2.03 years, while in the ondansetron group, it was 33.25 ± 2.39 years. Differences were observed in body weight, height, and BMI between the two groups. The incidence of PONV was significantly lower in the haloperidol group (2.5%) compared to the ondansetron group (30%) (p = 0.001). Conclusion: Intravenous haloperidol is more effective in reducing PONV incidence compared to ondansetron in RA-SAB patients.