Rasio Trigliserida/High Density Lipoprotein sebagai Prediktor Kejadian Kardiovaskular Mayor selama 6 Bulan Paska Rawatan pada Pasien Infark Miokard Akut dengan Diabetes Melitus Tipe 2 di Rsup Haji Adam Malik Medan
dc.contributor.advisor | Hasan, Refli | |
dc.contributor.advisor | Akbar, Nizam Zikri | |
dc.contributor.advisor | Nasution, Ali Nafiah | |
dc.contributor.advisor | Haykal, Teuku Bob | |
dc.contributor.advisor | Sarastri, Yuke | |
dc.contributor.author | Taufik, Yasdika Imam | |
dc.date.accessioned | 2025-07-25T03:47:18Z | |
dc.date.available | 2025-07-25T03:47:18Z | |
dc.date.issued | 2025 | |
dc.identifier.uri | https://repositori.usu.ac.id/handle/123456789/107434 | |
dc.description.abstract | Background: Cardiovascular disease (CVD) remains the leading global cause of death, with coronary artery disease (CAD) and stroke contributing to 15 million deaths in 2016. Type 2 diabetes mellitus (DM) increases the risk of complex CAD, characterized by diffuse, calcified, and multivessel lesions. While the triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) ratio is a potential independent predictor of CVD, its prognostic value for mortality in diabetic CAD patients undergoing statin therapy remains unclear. This study aimed to analyze the association between the TG/HDL-C ratio and cardiovascular and all-cause mortality in this population. Methods: This cross-sectional analytical study examined the relationship between the TG/HDL-C ratio and major cardiovascular events in non-ST-elevation acute coronary syndrome (NSTE-ACS) patients with type 2 DM receiving statin therapy. Data were collected through clinical observation and medical records. Statistical analysis utilized the Chi-square or Fisher’s Exact test to assess associations, with statistical significance defined as p <0.05. Results: The study included 72 patients (72.2% male; mean age 58.6±8.5 years) with type 2 DM (mean duration 10.5±3.9 years) and acute coronary syndrome (61.1% NSTEMI). Among participants, 61.1% were smokers, 48.6% had hypertension, and lipid profiles revealed 100% hypertriglyceridemia, 87.5% elevated LDL, and 33.3% low HDL. A high TG/HDL ratio was observed in 72.2% of subjects and was significantly associated with major adverse cardiovascular events (OR=3.32; p=0.025), indicating a 3.32-fold higher risk in the high TG/HDL ratio group. Conclusion: The TG/HDL-C ratio can serve as an effective parameter for estimating the risk of MACE in ACS patients with T2DM. | en_US |
dc.language.iso | id | en_US |
dc.publisher | Universitas Sumatera Utara | en_US |
dc.subject | Sindroma Koroner Akut | en_US |
dc.subject | Diabetes Melitus | en_US |
dc.subject | Trigliserida | en_US |
dc.subject | High Density Lipoprotein | en_US |
dc.title | Rasio Trigliserida/High Density Lipoprotein sebagai Prediktor Kejadian Kardiovaskular Mayor selama 6 Bulan Paska Rawatan pada Pasien Infark Miokard Akut dengan Diabetes Melitus Tipe 2 di Rsup Haji Adam Malik Medan | en_US |
dc.title.alternative | Triglyceride/High-Density Lipoprotein Ratio as a Predictor of Major Cardiovascular Events Within 6 Months Post-Treatment in Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus at Haji Adam Malik General Hospital, Medan | en_US |
dc.type | Thesis | en_US |
dc.identifier.nim | NIM217041025 | |
dc.identifier.nidn | NIDN0003046101 | |
dc.identifier.nidn | NIDN0014048104 | |
dc.identifier.nidn | NIDN0020078502 | |
dc.identifier.nidn | NIDN0024038701 | |
dc.identifier.kodeprodi | 11103 | |
dc.description.pages | 105 | en_US |
dc.description.type | Tesis Magister | en_US |
dc.subject.sdgs | SDGs 3. Good Health And Well Being | en_US |
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Master Theses (Clinical Medicine) [1441]
Tesis Magister (Kedokteran Klinis)