Laporan Praktik Kerja Profesi Apoteker Farmasi Industri Di PT. Dankos Farma Jakarta Timur

Abstract

The Pharmacist Professional Work Practice (PKPA) in the pharmaceutical industry aims to provide direct experience for pharmacy graduates in understanding production processes, quality control, and the implementation of GMP (Good Manufacturing Practices) and CPOB (Cara Pembuatan Obat yang Baik). This PKPA was conducted at PT Dankos Farma in the non-betalactam solid dosage production department. Activities included the application of GMP/CPOB, In Process Control (IPC), Critical Process Parameters (CPP), Critical Quality Attributes (CQA), and involvement in process improvement initiatives. During the program, the author participated in downtime analysis of tablet press machines and proposed preventive maintenance, resulting in a reduction of downtime by approximately 20%. In addition, support was provided for Total Productive Maintenance (TPM) on stripping machines, which improved packaging efficiency by 15%. The outcomes of this PKPA highlight the crucial role of pharmacists in ensuring product quality, safety, and efficiency within pharmaceutical manufacturing processes. Keywords: PKPA, Pharmaceutical Industry, GMP, CPOB, IPC, CPP, CQA, TPM.