Uji Efektivitas Ekstrak curcuma dari Rimpang Kunyit (Curcuma domestica val.) terhadap Pertumbuhan Streptococcus viridans Secara In Vitro

Abstract

Streptococcus viridans is one of the normal flora found in the oral cavity. These bacteria can cause infection in dry socket and cause odontogenic infections in the oral cavity. Streptococcus viridans can cause the formation of dental plaque and caries. Steptococcus viridans can synthesize polysaccharides such as dextran from sucrose to form attachments with other bacteria so that they can colonize and form dental plaque which can cause dental caries. This study aims to determine the antibacterial effectiveness of curcuma extract from Turmeric (Curcuma domestica val.) Rhizomes on the Growth of Streptococcus viridans. This research is an in vitro laboratory experimental study. By using the curcuma extract treatment group from turmeric (Curcuma domestica val.) with concentrations of 5%, 10%, 20%, and 40% with clindamycin positive control and DMSO negative control. Test the effectiveness of curcuma extract from turmeric (Curcuma domestica val.) rhizome in a study using the Kirby-baurer disc diffusion method. Data were analyzed by One Way Anova test and Post Hoc Test. The results of data analysis using ANOVA showed a p-value of 0.00 in inhibition, which means that curcuma extract from turmeric (Curcuma domestica val.) rhizome can inhibit the growth of Streptococcus viridans. The results of this study showed the effectiveness with a strong category of curcuma extract from turmeric (Curcuma domestica val.) at concentrations of 20% and 40%. The average inhibition zone produced was 9.83 mm at a concentration of 5%, 11.20 mm at a concentration of 10%, 11.93 mm at a concentration of 20% and 12.60 mm at a concentration of 40%. From this study it was concluded that curcuma extract from turmeric rhizome (Curcuma domestica val.) has an antibacterial effect against Streptococcus viridans.