Hubungan Tingkat Depresi dengan Kualitas Hidup Pasien Stroke Iskemik di Rumah Sakit Prof. dr. Chairuddin Panusunan Lubis USU

Abstract

Background: Post-stroke depression (PSD) is the most common neuropsychiatric complication in stroke patients and contributes significantly to reduced quality of life. Although the global prevalence of PSD reaches about one-third of stroke survivors, comparative data in Indonesia remain limited. Objective: To determine the relationship between depression level and quality of life among ischemic stroke patients. Methods: This cross-sectional study employed a consecutive sampling method involving ischemic stroke patients attending the outpatient clinic of Prof. dr. Chairuddin P. Lubis Universitas Sumatera Utara Hospital, Universitas Sumatera Utara, Medan, 20155, Indonesia. Depression levels were assessed using the Indonesian version of the PHQ-9, while quality of life was measured using the Indonesian version of the WHOQOL-BREF questionnaire. Statistical correlation and significance tests were performed. Results: Of all respondents, 32.1% experienced post-stroke depression, comparable to the global prevalence (31–33%). No significant associations were found between depression level and demographic factors such as age, sex, occupation, or education (p>0.05). A strong negative correlation (r=–0,819; p<0,001) was observed between PHQ-9 and WHOQOL-BREF scores, indicating that higher depression severity was associated with lower quality of life. The physical domain was the most affected aspect. Conclusion: PSD appears to be universal and independent of demographic factors. Post-stroke Depression significantly correlates to reduced quality of life in ischemic stroke patients; therefore, depression screening and psychosocial interventions should be integrated into routine stroke management across all healthcare levels.