Doctoral Dissertations
Doctoral Dissertations
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Now showing items 121-140 of 179
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Penelitian Invitro VEGF, TNF-α dan MMP9 pada Kultur Sel HeLa yang Mendapat Ekstrak Etanol Buah Senduduk (MELASTOMA MALABATHRICUM L)
(Universitas Sumatera Utara, 2020)Background: Noncumminicable diseases are responsible for the majority of deaths worldwide, reflect both aging and growth of the population. And cancer expected to rank as the leading cause of death. Cervical cancer ... -
Uji In-Vitro Sel Punca Mesenkimal dalam Meregulasi CD11C Sel Denritik dan CD19 Sel-B Melalui Induksi CD4+CD25+FOXP3+ T-Regulator pada Lupus Eritematosus Sistemik
(Universitas Sumatera Utara, 2020)Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with an unclear pathogenesis, as well as a variable course of disease and prognosis. SLE pathogenesis is currently still unclear. However, ... -
Pengaruh Ekstrak Buah Mengkudu (Morinda Citrifolia) terhadap Kadar Malondialdehid, Nerve Growth Factor dan High Sensitivity C-Reactive Protelnpada Wanita Overactive Bladder
(Universitas Sumatera Utara, 2020)Latar Belakang: Overactive bladder (OAB) mempunyai prevalensi yang tinhhi yaitu 16-18% dari seluruh populasi. Selama ini penggunaan obat antimuskarinik sebagai pilihan pada penatalaksanaan OAB akan tetapi membutuhkan ... -
Model Estimasi National Institutes of Health Stroke Scale Berdasarkan Pemberian Suplementasi Vitamin A dan D, Melalui Modulasi Interleukin-1β dan Interleukin-10 pada Stroke Iskemik Akut
(Universitas Sumatera Utara, 2020)Latar Belakang: Dalam dekade terakhir, sejumlah penelitian telah meneliti hubungan antara konsentrasi vitamin D serum dan risiko kejadian serebrovaskular. Selain vitamin D, bukti terbaru menunjukkan bahwa vitamin A juga ... -
Pengaruh Sel Punca Mesenkimal Terhadap Angiotensin II TYPE 1 Receptor, Asam Hialuronat, Interleukin-10 dan Platelet-Derived Growth Factor-β pada Tikus Galur Wistar Model Fibrosis Hati
(Universitas Sumatera Utara, 2020)Latar belakang: Fibrosis hati sering dihubungkan dengan pembentukan jaringan parut, kerusakan parenkim hati, dan kegagalan organ. Sel punca yang berasal dari sirkulasi sel terutama sel punca mesenkimal (MSC) endogen dapat ... -
Pengaruh Pemberian Ekstrak Ethanol Daun Puguntano (Curanga fel-terrae Merr.) Terhadap Viabilitas Sel, Ekspresi Tumor Necrosis Factor-α dan Interleukin-1α pada Biakan Matriks Kolesteatoma Penderita Otitis Media Supuratif Kronis Tipe Atikoantral
(Universitas Sumatera Utara, 2020)Otitis Media Supuratif Kronis kronis dengan atau tanpa kolesteatoma adalah masalah utama yang sudah bersifat global dan itu menjadi beban terutama di negara-negara berkembang. Penelitian-penelitian menemukan bahwa ekstrak ... -
Pengaruh Ekstrak Ikan Gabus (Channa striata Bloch.) Dan Rejimen Eradikasi Terhadap Ekspresi Macrophage Migration Inhibitory Factor Dan Kadar Asymmetric Dimethylarginine Pada Tikus Model Gastritis Pylori
(Universitas Sumatera Utara, 2020)Background: Helicobacter pylori is a pathogenic bacteria that causes gastritis in about half of the world's population. The severity of gastritis is associated with the density of H. pylori, gastric mucosal injury, and ... -
Pengaruh Pemberian Madu Terhadap Perubahan Kadar Soluble Fms-Like Tyrosine Kinase (Sflt-1), Soluble Endoglin (Seng), Vascular Endothelial Growth Factor (Vegf), Placental Growth Factor (Plgf), Tumor Necrosis Factor Alpha (Tnf-Α), Dan Interleukin 6 (Il-6) Pada Tikus Model Preeklamsia
(Universitas Sumatera Utara, 2020)Preeclampsia is a systemic syndrome that occurs during pregnancy and after pregnancy, and affects 3-8% of pregnancies. Expression of angiogenesis factors, both pro angiogenic (VEGF and PIGF), and anti-angiogenic (sFlt-1 ... -
Peran Ekstrak Buah Andaliman (Zanthoxylum acantophodium DC) Terhadap Perubahan Kadar TNF-α, IL-6, COX-2 dan MMP-9 Pada Tikus Model Preeklampsia
(Universitas Sumatera Utara, 2020)Preeclampsia is a pregnancy-specific syndrome characterized by abnormal placental implantation that causes impaired immune system balance between CD + 4 pro-inflammatory cells and T-regulating cells. This imbalance ... -
Hubungan Ekspresi CD133, LGR5, CD166 Sel Punca Kanker Kolorektal dan CD163 Tumor Associated Macrophage Dengan Perbedaan Lokasi Kanker Kolorektal
(Universitas Sumatera Utara, 2020)Background: The chemotherapy resistance and recurrency of colorectal cancer (CRCs) is still a problem in colorectal management. Colorectal cancer stem cells (CR-CSCs) were considered having a role in this situation, due ... -
Analisis Polimorfisme Gen Tumor Necrosis Factor- –308 G/A dan Kadar Tumor Necrosis Factor- Dengan Volume Otak pada Orang Dengan Skizofrenia
(Universitas Sumatera Utara, 2020)Background: There are three theories related to the etiology of schizophrenia, the first schizophrenia is a neurodevelopmental disease, second is a neurodegenerative disease, and third is a progressive neurodevelopment ... -
Pengaruh Pemberian Ekstrak Nigella Sativa Terhadap pH Vagina, Berat Badan, Koloni Jamur Candida Albicans, IgM dan IgG Anti-Kandida Metode Elisa pada Tikus Galur Wistar Betina Model Kandididasis Vulvovaginalis
(Universitas Sumatera Utara, 2020)Background: Vulvovaginal candidiasis (VVC) is a disease caused by Candida, which is mostly caused by Candida albicans. If not treated early, this disease can occur infertility complications in women who are sexually ... -
Hubungan Polimorfisme IL8-251 T>A dan IL8+781 C>T dengan Kadar IL8 dan Gastritis Helicobacter Pylori pada Anak
(Universitas Sumatera Utara, 2020)Aim To investigate the effects of interleukin-8 (IL-8) -251 T/A and +781 C/T polymorphism on the risk of Helicobacter pylori- infection gastritis in children, and the IL-8 level of children with or without gastritis H. ... -
Efek Curcumin Terhadap Faktor Pengencer Darah, VAS, Kadar COX-2, IL-10, MDA, SOD, sFlt-1 dan VEGF pada Pasien Preeklampsia yang Menjalani Seksio Sesarea dengan Anestesi Spinal
(Universitas Sumatera Utara, 2020)Background: WHO states that preeclampsia is the second leading cause of maternal morbidity and mortality. Clinical symptoms of preeclampsia is hypertension, pain in the pit of the stomach and bleeding that may occur due ... -
Efek Ekstrak Ikan Gabus (Channa striata) Terhadap Vascular Endothelial Growth Factor dan Nitric Oxide pada Angiogenesis Serebral Tikus Galur Sprague - Dawley Model Stroke Iskemik
(Universitas Sumatera Utara, 2020)Backgound: Changes in lifestyle due to modernization and globalization tend to increase the risk of vascular diseases such as coronary heart disease and stroke. Currently one of the ischemic stroke therapies is tissue ... -
Efek Suplementasi Vitamin D Terhadap Polineuropati Diabetik Melalui Modulasi Jalur Aldose Reduktase dan Interleukin–8
(Universitas Sumatera Utara, 2020)Background: Diabetic neuropathy is most commonly found in developing countries. The most common manifestation of DN is DPN. Activation of the polyol pathway is associated with increased activity of AR, which is involved ... -
Pengaruh Suplementasi Kolekalsiferol Terhadap Kadar 25(OH)D Serum dan Efektifitas Terapi pada Subjek Pengguna Amphetamine Type Stimulant
(Universitas Sumatera Utara, 2020)Latar belakang: Kolekalsiferol berperan penting dalam perkembangan fungsi otak dan gangguan-gangguan neuropsikiatri, hal ini dikaitkan dengan keterlibatan kolekalsiferol dalam berbagai proses otak termasuk berperan penting ... -
Hubungan Imunoekspresi IFN-γ dan IL-4 pada Aspirat Penderita Limfadenitis Tuberkulosis dengan Gambaran Dark Specks dan Dark Oval Bodies
(Universitas Sumatera Utara, 2019)Latar Belakang: Kami memperhatikan adanya kasus-kasus yang secara sitologis didiagnosis sebagai limfadenitis kronis biasa yang tidak dapat diobati dengan antibiotika biasa, tetapi berhasil dengan obat anti-tuberkulosis ... -
Perbandingan Efek Minyak Atsiri Daun Kemangi dan Fluoxetine Sebagai Antidepresan pada Mencit Depresi Ditinjau dari Kadar Kortisol dan Serotonin Darah
(Universitas Sumatera Utara, 2020)Background: Depression is one of a serious mental health problem. From year to year, the prevalence of depression continuous to increase. The impact of depression is really massive, starting from the declining of work ... -
Polimorfisme G894t Gene Nitric Oxide Synthase 3 dan Kadar Nitric Oxide pada Diabetes Melitus Tipe 2 dengan Hipertensi pada Suku Batak
(Universitas Sumatera Utara, 2019)Aim To assess endothelial nitric oxide synthase (eNOS) gene (G894T) polymorphism and NO level in hypertensive diabetic Bataknese patient. Methods Hospital-based, case control study (hypertensive and normotensive diabetic ...
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