Doctoral Dissertations
Doctoral Dissertations
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Now showing items 141-160 of 179
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Analisis Polimorfisme Gen Adiponektin +45T/G dan +276G/T) dan Kadar Adiponektin Pasien dengan Aliran Lambat Pembuluh Darah Koroner pada Suku Aceh
(Universitas Sumatera Utara, 2019)Background: Until now, the etiology and mechanism of SCF have not been fully known. But looking at it through histopathology, microvascular inflammation has been found. APN is an important modulator of inflammation that ... -
Hubungan Gen HLA-DRB1 dan Faktor Lingkungan Terhadap Kejadian Penyakit Jantung Reumatik pada Anak
(Universitas Sumatera Utara, 2019)Introduction Rheumatic heart disease (RHD) and RHD reactivation are still the most common cause of acquired heart disease and mortality in developing countries because of the permanent damage to the heart valve tissue. ... -
Pengaruh Suplementasi Kalsium Terhadap Kadar Timbal Darah dan Memori Jangka Pendek Anak yang Terpapar Timbal Secara Kronis
(Universitas Sumatera Utara, 2019)Objective : Lead poisoning can irreversibly impair the children’s brain, even with blood lead levels (BLLs) as low as 5 g/dL. Lead competes with Ca2+ in calmodulin binding and disturb the enzyme activity in transcription ... -
Efek Ekstrak Daun Poguntano (Picria fel-terrae Merr.) Terhadap Kadar Protein Proinflamasi pada Tikus Galur Wistar Model Rinosinusitis Akut Bakterial
(Universitas Sumatera Utara, 2019)Acute bacterial rhinosinusitis (ABRS) is one of the most common inflammatory diseases to be investigated. Most acute rhinosinusitis generally of viral origin, only around 0.5-2% becomes acute bacterial rhinosinusitis. ... -
Peran Polimorfisme Gen Reseptor Vitamin D FokI rs2228570, ApaI rs7975232, TaqI rs731236 dan Antibodi IgM Anti-PGL-1 Serta Faktor-Faktor Risiko untuk Mengalami Kusta pada Narakontak Serumah
(Universitas Sumatera Utara, 2019)Background: Leprosy is a chronic infectious disease with dermatologic and neurologic manifestations, which is caused by Mycobaterium leprae and can be transmitted through inhalation, direct skin contact, ingestion, ... -
Pengaruh Mesenchymal Stem Cells (MSCs) Hipoksia dan MSCs Conditioned-Medium dengan Teknik Omental Patch Terhadap Derajat Adhesi Peritoneal
(Universitas Sumatera Utara, 2019)Background: Peritoneal adhesions can cause problems especially in post-laparotomy due to peritonitis. The most common cause of adhesions is actions involving the small intestine, large intestine, appendix, and uterus. ... -
Penggunaan Vascular Endothelial Growth Factor dan Asam Folat Sebagai Prediktor Apendisitis Komplikata pada Hewan Coba Oryctolagus Cuniculus
(Universitas Sumatera Utara, 2019)Appendicitis is the most common abdominal disease that requires surgery in children. The mortality rate in appendicitis is greatly affected by rupture or leakage of the appendix. In establishing the diagnosis of appendicitis, ... -
Efek Latihan Isometrik Otot Plantar Fleksor Terhadap Aktivitas Osteoblast Diukur dengan Bone Specific Alkaline Phosphatase dan Pembentukan Kalus pada Pasien Post Open Reduction Internal Fixation Fraktur Tibia Non Articular
(Universitas Sumatera Utara, 2019)Background: Post operative non-articular tibia fracture several problems that can occur include; pain, muscles atrophy, muscles weakness, joint stiffness, delayed union, and non-union that makes patients limited in their ... -
Hubungan Aktivitas NOTCH1 Terhadap Ekspresi Petanda Sel Punca Kanker CD133, Proliferasi Sel Tumor (Ki-67), dan Histology Grading pada Cutaneous Squamous Cell Carcinoma
(Universitas Sumatera Utara, 2019)Background: Cutaneous squamous cell carcinoma (cSCC) is a malignant tumour derived from keratinocytes from suprabasal epidermis. Notch1 gene can function as oncogene or tumor suppressor gene. If Notch1 signaling pathway ... -
Pengaruh Terapi Progesterone pada Cidera Otak Berat Non Operatif Terhadap Perubahan Kadar Serum S-100β, Interleukin 6, dan Aquaporin 4
(Universitas Sumatera Utara, 2019)BACKGROUND: Traumatic Brain Injury (TBI) consists of two processes called primary and secondary injury. Secondary injury on TBI involves a lot of complexes factors of cellular response to the impact of post primary injury. ... -
Korelasi Matriks Metalloproteinase-9, High Sensitivity Creactive Protein dan Glutamat Serum dengan Intensitas Nyeri Setelah Pemberian Flunarizin pada Penderita Tension-Type Headache Kronik
(Universitas Sumatera Utara, 2018)Background: Despite the progress in basic and clinical research in recent years, the origin of pain in TTH is unknown. The role of inflammation has also been investigated in TTH. Several pieces of evidence show that ... -
Pengaruh Pemberian Ekstrak Etanol Daun Salam (Syzygium polyanthum Wight Walp) Terhadap Penurunan Kadar Regenerating Islet–Derived Protein 3 Beta (REG3β), C-Reactive Protein (CRP) dan Myeloperoxidase (MPO) pada Kardiomiosit Tikus Galur Wistar Model Sindroma Koroner Akut
(Universitas Sumatera Utara, 2019)The highest prevalence for cardiovascular disease is coronary heart disease (CHD) which is a big problem due to high mortality and mobility rates. This study aims to prove the effect of ethanol extract of bay leaves ... -
Pengaruh Latihan Persiapan Khusus dan Sport Massage Terhadap Kemampuan Komponen Fisik Dasar, Glutathione Peroxidase, Asam Laktat, Gas Darah, Intensitas Nyeri dan Waktu Tempuh Pelari 200 Meter
(Universitas Sumatera Utara, 2017)Background: Movement of explosive power at 200 meter runner potential to generate free radicals. Energy source in the 200-meter runner on the pattern of motion derived from predominantly anaerobic metabolism that could ... -
Pengaruh Pemberian Tiamin Terhadap Kadar Enzim Catechol-O-Methyltransferase (COMT) dan Skor Amsterdam Preoperative Anxiety and Information Scale (APAIS) pada Pasien Ansietas Preoperatif
(Universitas Sumatera Utara, 2019)Backgound. Preoperative anxiety increases intraoperative and postoperative morbidity and mortality. Anxiolytic premedication drugs that exist so far have adverse side effects. Methods. We conducted a study of thiamine ... -
Pengaruh Polimorfisme THR256SER Gen α-2 Heremans Schmid Glycoprotein Terhadap Ketahanan Hidup Pasien Hemodialisis Kronik (Fokus pada Kajian Molekuler Fetuin-A dan Interleukin-6 pada Kalsifikasi Vaskular)
(Universitas Sumatera Utara, 2019)Background: Vascular calcification is a strong predictor for cardiovascular disease and all-cause mortality in chronic kidney disease patients on hemodialysis. The mechanism remains unclear, but recently, it is focused ... -
Analisis Ekspresi Heat Shock Protein 70, Caspase 3 dan Komposisi Mikrobiota pada Penderita Kanker Kolorektal
(Universitas Sumatera Utara, 2016)Colorectal cancer is proven to be the fourth most cancer worldwide and as the second in United States. In Indonesia, from the several centre reports increase case per years This study was conducted as initial study to ... -
Pengaruh Jumlah Sel Kumulus, Ekspresi Reseptor LH, Caspase 3 dan p53 pada Bermacam Pola Sel Kumulus Terhadap Keberhasilan Maturasi Oosit Pada Proses In Vitro Maturasi yang Dilakukan Vitrifikasi
(Universitas Sumatera Utara, 2017)Objective: to analyze the influence of the number of cumulus cell and the expression of LH receptor, caspase 3, p53 on the success in oocyte maturation in the process of in vitro maturation after vitrification. Method: ... -
Hubungan Kadar Vitamin D dan Tissue Inhibitor Metalloproteinase 1 (TIMP-1) dengan Matrix Metalloproteinase 9 (MMP-9) pada Penyakit Paru Obstruktif Kronik (PPOK)
(Universitas Sumatera Utara, 2019)Background: Chronic Obstructive Pulmonary Disease (COPD) is still the main causes of chronic morbidity and mortality in the world. Smoking is a major risk factor for COPD. The prevalence of COPD disease is directly related ... -
Pengaruh Polimorfisme NRG-1 rs35753505 C/T Terhadap Kadar Neuregulin 1 pada Neonatus Kurang Bulan Sesuai Masa Kehamilan
(Universitas Sumatera Utara, 2019)Objective : Handling premature babies is still a challenge nowadays. The biggest challenge is how to reduce the risk of morbidity so that later it will reduce longterm morbidity so that premature babies can grow optimally. ... -
Status Endotel Pasien dengan Demam Berdarah Dengue
(Universitas Sumatera Utara, 2019)Background: Dengue fever is a disease with the most serious consequence of mosquito-borne infection worldwide. The pathophysiology of DHF in human is complex which involve endothelial cell activation and impaired endothelial ...
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