Doctoral Dissertations

Now showing items 181-183 of 183

Hubungan Polimorfisme Genetik CYP2A6 dan CYP2A13 dengan Metabolisme Nicotine pada Pasien Kanker Paru di Kalangan Perokok Suku Batak

Soeroso, Noni Novisari (Universitas Sumatera Utara, 2018)

Background: Nicotine is main psychoactive ingredient in tobacco which caused the addiction, among smokers. In humans, the majority of nicotine is metabolized to cotinine (COT), and forth is metabolized to trans-3′-hydr ...
Penurunan Kadar Matriks Metalloproteinase-9 dan D-Dimer Plasma setelah Pemberian Bromelin dan Korelasinya dengan Luaran Klinis pada Stroke Iskemik Akut

Sinurat, Puji Pinta Omas (Universitas Sumatera Utara, 2018)

Expression of Matrix Metalloproteinase9 (MMP9) due to ischemic conditions in the brain causes damage to the blood brain barrier, edema and widespread brain damage and is thought to worsen the clinical outcome. D-dimer as ...
Hubungan Variasi Gen Sodium Channel 1 Alpha (SCN1A) dengan Depresi pada Penderita Epilepsi dan Penderita Migren

Lestari, Nova Dian (Universitas Sumatera Utara, 2018)

Background: Epilepsy and migraine are paroxysmal neurological disorder resulting from abnormal cellular excitability. Voltage-gated sodium channels (VGSCs) are key mediators of intrinsic neuronal excitability. Mutation of ...