Doctoral Dissertations

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Hubungan dan Rasio Partikulat Mater 10 terhadap Metilasi DNA Gen p53 dan Jumlah Black Dots dalam Nuklei Sel Epitel Bukal Pekerja Daur Ulang Tempat Pembuangan Akhir Sampah Kota Medan

Intan, T Kemala (Universitas Sumatera Utara, 2024)

Open landfill sites are frequently-exposed areas of particulate matter (PM10) with various types of particulates. This variation is due to the waste disposal management activity including burning, fermentations, movements ...
Hubungan Sel Eosinophil dan Massa Eosinophil dengan Keberadaan Atypical Mycobacterium pada Biopsi Aspirasi Lymphadenitis

Hastuti, Neni Wahyu (Universitas Sumatera Utara, 2024)

Background. The diagnosis of tuberculous lymphadenitis on aspiration biopsy preparations can be established based on the presence of dark specks (DS). DS is rather dark-colored stuff contained in eosinophilic granular ...
Efek Pemberian Piracetam pada Kadar dan Ekspresi Interleukin-6, Glial Fibrillary Acidic Protein, Brain-Derived Neurotrophic Factor, mRNA Gelsolin, mRNA GluN3A, dan mRNA Calmodulin-2, pada Jaringan Otak Janin Tikus Model Periventricular Leukomalacia

Aldiansyah, Dudy (Universitas Sumatera Utara, 2024)

Introduction: Periventricular leukomalacia (PVL) is commonly found in cases of hypoxic ischemic encephalopathy, occurring due to perinatal damage to the cerebral cortex. This damage may be in the form of hypoxia, metabolic ...
Pengaruh Metamizole terhadap Kadar IL-18, NGAL, Myeloperoxidase dan Gambaran Histopatologi pada Tikus Wistar Model Renal Ischemia-Reperfusion Injury

Kadar, Dhirajaya Dharma (Universitas Sumatera Utara, 2024)

Background: Renal ischaemia-reperfusion injury (RIRI) is a common kidney procedure complication due to temporary blood flow interruption, leading to kidney injuries. This study aimed to analyze the effect of metamizole ...
Peran Polimorfisme E670G (rs505151) Gen PCSK9 dan Perbandingan antara Kadar PCSK9 terhadap Severitas Lesi Koroner pada Penderita Penyakit Jantung Koroner

Andra, Cut Aryfa (Universitas Sumatera Utara, 2024)

Background: Cardiovascular disease, the most prevalent health issue globally, continues to escalate in both developed and developing nations. A notable method for assessing the risk of coronary artery disease (CAD) involves ...
Pengaruh Pemberian Kombinasi Ekstrak Gambir (Uncaria gambier Roxb) dan Angiotensin Receptor Blocker (ARB) terhadap Kadar Transforming Growth Factor-Beta (TGF- β), Ekspresi Nadph Oxidase 4 (NOX4) aan Derajat Glomerulosklerosis pada Tikus Galur Wistar Model Sindrom Nefrotik

Siregar, Rosmayanti Syafriani (Universitas Sumatera Utara, 2024)

Background: Nephrotic syndrome (NS) is the most common glomerular disease found in children. Proteinuria induces profibrotic and proinflammatory cytokines that play a role in extracellular matrix synthesis, differentiation, ...
Pengaruh Fraksi Etil Asetat dari Ekstrak Bawang Dayak (Eleutherine bulbosa (Mill.) Urb) terhadap Sel Kanker Payudara T47D yang Dipaparkan Estrogen

Lubis, Lokot Donna (Universitas Sumatera Utara, 2024)

Background: Breast cancer is the most common cause of cancer death in women and the fifth leading cause of all cancer deaths. In Indonesia, the high incidence of breast cancer is also accompanied by a low rate of treatment ...
Efek Pemberian Isolat Oleuropein terhadap Kadar Apoptosis Inducing Factor, Glial Acidic Fibrillary Protein, Matrix Metalloproteinase-9 dan High Mobility Group Box-1 pada Tikus Model Cedera Otak Traumatik

Arsyad, Abdurrahman Mousa (Universitas Sumatera Utara, 2023)

Background : The incidence of head injuries in the world is currently touching 250 cases per 100,000 population worldwide. Two types of cell death can occur in head injury, namely necrosis and apoptosis. Polyphenols are ...
Efek Ekstrak Ethanol Daun Binahong (Anredera cordifolia) sebagai Anti Obesitas terhadap Kadar ERK, PI3-K serta Ekspresi PPAR γ pada Tikus Putih Galur Wistar Model Obesitas

Rusdiana, Rusdiana (Universitas Sumatera Utara, 2023)

Background : Currently, obesity is a global health problem due to the high mortality rate of disease complications caused by obesity. Losing weight means reducing complications, by inhibiting the processes and pathways ...
Pengaruh Sekretom Sel Punca Mesenkimal Hipoksia terhadap Percepatan Penyembuhan Luka Pasca Penempelan Split Thickness Skin Graft pada Model Luka Bakar Derajat Tiga

Prananda, Arya Tjipta (Universitas Sumatera Utara, 2023)

Background: Effective wound management is an important determinant of survival and prognosis of third-degree burn patients. Recently, autologous skin grafting techniques (skin grafts) such as split-thickness grafts (STSG) ...
Pengaruh Tetes Mata Curcumin terhadap Penyembuhan Luka Laserasi Lamellar Kornea Ditinjau dari Penurunan Ekspresi IL-1, TNF-α, NFκB serta Perbaikan Gambaran Histopatologi Kornea Rattus Norvegicus

Zubaidah, T Siti Harilza (Universitas Sumatera Utara, 2024)

Backgroung Corneal lamellar lacerations are emergencies in ophthalmology that involve partial thickness of the cornea. Curcumin is a polyphenol derived from Rhizopus which has the ability to accelerate wound healing Purpose To ...
Pengaruh Pemberian Ekstrak Etanol Jahe Merah (ZingibeR officinale Rosc. Var. RUBRUM) terhadap Kadar Interleukin 6 (IL-6), Interleukin 10 (IL-10) Tumor Necrotic Factor α (TNF- α) dan C-Reactive Protein (C-RP) pada Mencit (Mus musculus) Model Ansietas

Dania, Ira Aini (Universitas Sumatera Utara, 2023)

Background: Anxiety disorders, with their psychological and physical symptoms, lead to a reduction in sufferers' quality of life and immunity. Moreover, their high prevalence globally, including in North Sumatra, has ...
Hubungan Polimorfisme IL-1β-1903 C>T dan +3954 C>T dengan Kadar IL-1β terhadap Kejadian Anemia Defisiensi Besi pada Anak dengan Infeksi Helicobacter Pylori

Nafianti, Selvi (Universitas Sumatera Utara, 2023)

Background: Helicobacter pylori (H. pylori) infection has long been known to cause iron deficiency anemia. However, the data above shows that not all children infected with H. pylori develop iron deficiency anemia. The ...
Efek Pemberian Sekretom Sel Punca Mesenkimal terhadap Ekspresi NF-kB, Kadar TNF-α, IL-6, IL-10, IL-4 dan Ekspresi PD-1, PD-L1 serta Survival Rate Tikus Model Sepsis

Sari, Mutiara Indah (Universitas Sumatera Utara, 2023)

Introduction: Currently worldwide, the mortality rate due to sepsis is still high. The uncontrolled inflammatory response with the imbalance of pro-inflammatory and anti-inflammatory as well as the increased release of ...
Efek Ekstrak Etanol Daun Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) terhadap Kadar Glukosa Darah, Tumor Necrosis Factor-a, Interleukin-6 Serum serta Ekspresi Pospho-Amp Activated Protein Kinase Otot Skelet pada Tikus Model Diabetes

Lestari, Ira Cinta (Universitas Sumatera Utara, 2023)

Background: Patients with diabetes mellitus experience hyperglycemia conditions that can activate pro-inflammatory cytokines such as TNF-α and IL-6, which play a role in the incidence of insulin resistance and the development ...
Efek Ekstrak Etanol Daun Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) terhadap Kadar Glukosa Darah, Tumor Necrosis Factor-Α, Interleukin-6 Serum serta Ekspresi Pospho-AMP Activated Protein Kinase Otot Skelet pada Tikus Model Diabetes

Lestari, Ira Cinta (Universitas Sumatera Utara, 2023)

Background: Patients with diabetes mellitus experience hyperglycemia conditions that can activate pro-inflammatory cytokines such as TNF-α and IL-6, which play a role in the incidence of insulin resistance and the development ...
Analisis Peran Polimorfisme Gen CYP2R1 rs10741657, CYP27B1 rs10877012, Kadar Vitamin D pada Ibu Hamil Infeksi Laten Tuberkulosis terhadap Kadar Vitamin D, Katelisidin, Toll- Like Receptor 2, dan Interferon g pada Bayi Baru Lahir

Meirina, Fathia (Universitas Sumatera Utara, 2023)

Background. Latent Tuberculosis Infection (LTBI) in pregnant women can progress to active TB infection and potentially infect their newborns such that infection-mediated immune responses may affect the child's immune ...
Pengaruh Pemberian Ekstrak Bawang Putih (Allium sativum L.), Ekstrak Daun Mint (Mentha piperita L.), dan Kombinasi Keduanya terhadap Ekspresi Gen SFTP-A1, Kadar Glutation, dan Makrofag Alveolar Tikus Model Perokok

Savira, Maya (Universitas Sumatera Utara, 2023)

Background. Exposure to secondhand smoke is the leading cause of death worldwide and is known as a risk factor in the development and pathogenesis of several diseases, most of which are respiratory and cardiovascular ...
Pengaruh Intra-Arterial Heparin Flushing terhadap Hasil Audiometri Nada Murni, Distortion Product Otoacoustic Emission, Kadar Prestin, dan Kadar Vascular Endothelial Growth Factor pada Pasien dengan Gangguan Pendengaran di RSPAD Gatot Subroto

Daulay, Elvita Rahmi (Universitas Sumatera Utara, 2023)

Background: Several causes of sensorineural hearing loss are known to cause cochlear vascular changes such as changes in blood flow, increased vascular permeability, and vasoconstriction. The sensorineural type hearing ...
Pengaruh Pemberian Sekretom Sel Punca Mesenchymal Hipoksia terhadap Ekspresi Gen Vascular Endothelial Derived Growth Factor (VEGF), Platelet Derived Growth Factor (PDGF), Thrombospondin-4 (TSP-4) dan Angiogenesis pada Tikus Model Diabetes Mellitus dengan Hindlimb Ischemia

Sazli, Brama Ihsan (Universitas Sumatera Utara, 2023)

Introduction: Diabetes is a major health problem in the world where one of the complications is Peripheral Arterial Disease (PAD). Mesenchymal stem cells are reported to have several growth factors that play a role in ...

Doctoral Dissertations

Doctoral Dissertations

Recently added

Hubungan dan Rasio Partikulat Mater 10 terhadap Metilasi DNA Gen p53 dan Jumlah Black Dots dalam Nuklei Sel Epitel Bukal Pekerja Daur Ulang Tempat Pembuangan Akhir Sampah Kota Medan ﻿

Hubungan Sel Eosinophil dan Massa Eosinophil dengan Keberadaan Atypical Mycobacterium pada Biopsi Aspirasi Lymphadenitis ﻿

Efek Pemberian Piracetam pada Kadar dan Ekspresi Interleukin-6, Glial Fibrillary Acidic Protein, Brain-Derived Neurotrophic Factor, mRNA Gelsolin, mRNA GluN3A, dan mRNA Calmodulin-2, pada Jaringan Otak Janin Tikus Model Periventricular Leukomalacia ﻿

Pengaruh Metamizole terhadap Kadar IL-18, NGAL, Myeloperoxidase dan Gambaran Histopatologi pada Tikus Wistar Model Renal Ischemia-Reperfusion Injury ﻿

Peran Polimorfisme E670G (rs505151) Gen PCSK9 dan Perbandingan antara Kadar PCSK9 terhadap Severitas Lesi Koroner pada Penderita Penyakit Jantung Koroner ﻿

Pengaruh Pemberian Kombinasi Ekstrak Gambir (Uncaria gambier Roxb) dan Angiotensin Receptor Blocker (ARB) terhadap Kadar Transforming Growth Factor-Beta (TGF- β), Ekspresi Nadph Oxidase 4 (NOX4) aan Derajat Glomerulosklerosis pada Tikus Galur Wistar Model Sindrom Nefrotik ﻿

Pengaruh Fraksi Etil Asetat dari Ekstrak Bawang Dayak (Eleutherine bulbosa (Mill.) Urb) terhadap Sel Kanker Payudara T47D yang Dipaparkan Estrogen ﻿

Efek Pemberian Isolat Oleuropein terhadap Kadar Apoptosis Inducing Factor, Glial Acidic Fibrillary Protein, Matrix Metalloproteinase-9 dan High Mobility Group Box-1 pada Tikus Model Cedera Otak Traumatik ﻿

Efek Ekstrak Ethanol Daun Binahong (Anredera cordifolia) sebagai Anti Obesitas terhadap Kadar ERK, PI3-K serta Ekspresi PPAR γ pada Tikus Putih Galur Wistar Model Obesitas ﻿

Pengaruh Sekretom Sel Punca Mesenkimal Hipoksia terhadap Percepatan Penyembuhan Luka Pasca Penempelan Split Thickness Skin Graft pada Model Luka Bakar Derajat Tiga ﻿

Pengaruh Tetes Mata Curcumin terhadap Penyembuhan Luka Laserasi Lamellar Kornea Ditinjau dari Penurunan Ekspresi IL-1, TNF-α, NFκB serta Perbaikan Gambaran Histopatologi Kornea Rattus Norvegicus ﻿

Pengaruh Pemberian Ekstrak Etanol Jahe Merah (ZingibeR officinale Rosc. Var. RUBRUM) terhadap Kadar Interleukin 6 (IL-6), Interleukin 10 (IL-10) Tumor Necrotic Factor α (TNF- α) dan C-Reactive Protein (C-RP) pada Mencit (Mus musculus) Model Ansietas ﻿

Hubungan Polimorfisme IL-1β-1903 C>T dan +3954 C>T dengan Kadar IL-1β terhadap Kejadian Anemia Defisiensi Besi pada Anak dengan Infeksi Helicobacter Pylori ﻿

Efek Pemberian Sekretom Sel Punca Mesenkimal terhadap Ekspresi NF-kB, Kadar TNF-α, IL-6, IL-10, IL-4 dan Ekspresi PD-1, PD-L1 serta Survival Rate Tikus Model Sepsis ﻿

Efek Ekstrak Etanol Daun Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) terhadap Kadar Glukosa Darah, Tumor Necrosis Factor-a, Interleukin-6 Serum serta Ekspresi Pospho-Amp Activated Protein Kinase Otot Skelet pada Tikus Model Diabetes ﻿

Efek Ekstrak Etanol Daun Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) terhadap Kadar Glukosa Darah, Tumor Necrosis Factor-Α, Interleukin-6 Serum serta Ekspresi Pospho-AMP Activated Protein Kinase Otot Skelet pada Tikus Model Diabetes ﻿

Analisis Peran Polimorfisme Gen CYP2R1 rs10741657, CYP27B1 rs10877012, Kadar Vitamin D pada Ibu Hamil Infeksi Laten Tuberkulosis terhadap Kadar Vitamin D, Katelisidin, Toll- Like Receptor 2, dan Interferon g pada Bayi Baru Lahir ﻿

Pengaruh Pemberian Ekstrak Bawang Putih (Allium sativum L.), Ekstrak Daun Mint (Mentha piperita L.), dan Kombinasi Keduanya terhadap Ekspresi Gen SFTP-A1, Kadar Glutation, dan Makrofag Alveolar Tikus Model Perokok ﻿

Pengaruh Intra-Arterial Heparin Flushing terhadap Hasil Audiometri Nada Murni, Distortion Product Otoacoustic Emission, Kadar Prestin, dan Kadar Vascular Endothelial Growth Factor pada Pasien dengan Gangguan Pendengaran di RSPAD Gatot Subroto ﻿

Pengaruh Pemberian Sekretom Sel Punca Mesenchymal Hipoksia terhadap Ekspresi Gen Vascular Endothelial Derived Growth Factor (VEGF), Platelet Derived Growth Factor (PDGF), Thrombospondin-4 (TSP-4) dan Angiogenesis pada Tikus Model Diabetes Mellitus dengan Hindlimb Ischemia ﻿

Hubungan dan Rasio Partikulat Mater 10 terhadap Metilasi DNA Gen p53 dan Jumlah Black Dots dalam Nuklei Sel Epitel Bukal Pekerja Daur Ulang Tempat Pembuangan Akhir Sampah Kota Medan

Hubungan Sel Eosinophil dan Massa Eosinophil dengan Keberadaan Atypical Mycobacterium pada Biopsi Aspirasi Lymphadenitis

Efek Pemberian Piracetam pada Kadar dan Ekspresi Interleukin-6, Glial Fibrillary Acidic Protein, Brain-Derived Neurotrophic Factor, mRNA Gelsolin, mRNA GluN3A, dan mRNA Calmodulin-2, pada Jaringan Otak Janin Tikus Model Periventricular Leukomalacia

Pengaruh Metamizole terhadap Kadar IL-18, NGAL, Myeloperoxidase dan Gambaran Histopatologi pada Tikus Wistar Model Renal Ischemia-Reperfusion Injury

Peran Polimorfisme E670G (rs505151) Gen PCSK9 dan Perbandingan antara Kadar PCSK9 terhadap Severitas Lesi Koroner pada Penderita Penyakit Jantung Koroner

Pengaruh Pemberian Kombinasi Ekstrak Gambir (Uncaria gambier Roxb) dan Angiotensin Receptor Blocker (ARB) terhadap Kadar Transforming Growth Factor-Beta (TGF- β), Ekspresi Nadph Oxidase 4 (NOX4) aan Derajat Glomerulosklerosis pada Tikus Galur Wistar Model Sindrom Nefrotik

Pengaruh Fraksi Etil Asetat dari Ekstrak Bawang Dayak (Eleutherine bulbosa (Mill.) Urb) terhadap Sel Kanker Payudara T47D yang Dipaparkan Estrogen

Efek Pemberian Isolat Oleuropein terhadap Kadar Apoptosis Inducing Factor, Glial Acidic Fibrillary Protein, Matrix Metalloproteinase-9 dan High Mobility Group Box-1 pada Tikus Model Cedera Otak Traumatik

Efek Ekstrak Ethanol Daun Binahong (Anredera cordifolia) sebagai Anti Obesitas terhadap Kadar ERK, PI3-K serta Ekspresi PPAR γ pada Tikus Putih Galur Wistar Model Obesitas

Pengaruh Sekretom Sel Punca Mesenkimal Hipoksia terhadap Percepatan Penyembuhan Luka Pasca Penempelan Split Thickness Skin Graft pada Model Luka Bakar Derajat Tiga

Pengaruh Tetes Mata Curcumin terhadap Penyembuhan Luka Laserasi Lamellar Kornea Ditinjau dari Penurunan Ekspresi IL-1, TNF-α, NFκB serta Perbaikan Gambaran Histopatologi Kornea Rattus Norvegicus

Pengaruh Pemberian Ekstrak Etanol Jahe Merah (ZingibeR officinale Rosc. Var. RUBRUM) terhadap Kadar Interleukin 6 (IL-6), Interleukin 10 (IL-10) Tumor Necrotic Factor α (TNF- α) dan C-Reactive Protein (C-RP) pada Mencit (Mus musculus) Model Ansietas

Hubungan Polimorfisme IL-1β-1903 C>T dan +3954 C>T dengan Kadar IL-1β terhadap Kejadian Anemia Defisiensi Besi pada Anak dengan Infeksi Helicobacter Pylori

Efek Pemberian Sekretom Sel Punca Mesenkimal terhadap Ekspresi NF-kB, Kadar TNF-α, IL-6, IL-10, IL-4 dan Ekspresi PD-1, PD-L1 serta Survival Rate Tikus Model Sepsis

Efek Ekstrak Etanol Daun Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) terhadap Kadar Glukosa Darah, Tumor Necrosis Factor-a, Interleukin-6 Serum serta Ekspresi Pospho-Amp Activated Protein Kinase Otot Skelet pada Tikus Model Diabetes

Efek Ekstrak Etanol Daun Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) terhadap Kadar Glukosa Darah, Tumor Necrosis Factor-Α, Interleukin-6 Serum serta Ekspresi Pospho-AMP Activated Protein Kinase Otot Skelet pada Tikus Model Diabetes

Analisis Peran Polimorfisme Gen CYP2R1 rs10741657, CYP27B1 rs10877012, Kadar Vitamin D pada Ibu Hamil Infeksi Laten Tuberkulosis terhadap Kadar Vitamin D, Katelisidin, Toll- Like Receptor 2, dan Interferon g pada Bayi Baru Lahir

Pengaruh Pemberian Ekstrak Bawang Putih (Allium sativum L.), Ekstrak Daun Mint (Mentha piperita L.), dan Kombinasi Keduanya terhadap Ekspresi Gen SFTP-A1, Kadar Glutation, dan Makrofag Alveolar Tikus Model Perokok

Pengaruh Intra-Arterial Heparin Flushing terhadap Hasil Audiometri Nada Murni, Distortion Product Otoacoustic Emission, Kadar Prestin, dan Kadar Vascular Endothelial Growth Factor pada Pasien dengan Gangguan Pendengaran di RSPAD Gatot Subroto

Pengaruh Pemberian Sekretom Sel Punca Mesenchymal Hipoksia terhadap Ekspresi Gen Vascular Endothelial Derived Growth Factor (VEGF), Platelet Derived Growth Factor (PDGF), Thrombospondin-4 (TSP-4) dan Angiogenesis pada Tikus Model Diabetes Mellitus dengan Hindlimb Ischemia