Doctoral Dissertations
Doctoral Dissertations
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Hubungan HSP 70 dengan p53, Cytochrome C, Caspase 3 dan Kerusakan Koklea Melalui Heat Shock Respon Akibat Paparan Bising
(Universitas Sumatera Utara, 2015)Background. Noise is one of the factors of stress and often disturbing around our neighborhood. Exposure to high noise more than 85 dB and continuously can cause permanent damage Organ of Corti and the auditory nerve. The ... -
Efek Diet Indeks Glikemik Rendah dengan Campuran Tempe Kedelai terhadap Konsentrasi Tissue - Type Plasminogen Activator (t-PA) Antigen, Plasminogen Activator Inhibitor Tipe-1 (PAI-1) Antigen dan Lipid Plasma Wanita Obesitas Dewasa
(Universitas Sumatera Utara, 2007)Prevalenve of obese is rapidly becoming one of the most important medical and public health problems in countries worldwide, as well as in Indonesia Epidemiological studies liave reported a progressive increases in ... -
Hubungan Sel Myeloid-Derived Supressor, T Regulatori dan Carcinoma Associated Fibroblast dengan Grade Histopatologi Penderita Kanker Payudara Tripel Negatif Usia Muda sebagai Faktor Prediktor Keberhasilan Kemoterapi
(Universitas Sumatera Utara, 2023)Background: Breast cancer is a heterogeneous type of cancer due to variations in clinical picture, tumor biology behavior and response to chemotherapy. Patients with breast cancer at a young age are often associated with ... -
Hubungan antara Polimorfisme CTLA-4 -1661G>A dengan Kadar CTLA-4 dan Respons Virologis terhadap Pengobatan Tenofovir Disoproxil Fumarate pada Pasien Hepatitis B Kronik
(Universitas Sumatera Utara, 2023)Background: In chronic hepatitis B infection there is a weakening of T cell activity due to cell anergy which is characterized by poor cytotoxic T cell response, decreased cytokine production due to increased expression ... -
Peran Sensitisasi Protein Susu Sapi Melalui Aktifitas Limfosit Th-1 dan Th-2 serta Faktor Risiko Alergi dan Lingkungan dalam Terjadinya Mengi pada Bayi sampai dengan Usia 1 Tahun
(Universitas Sumatera Utara, 2014)Background: Allergic disease is an important issue because it occurs at all levels of society and increasing the number of events in the last three decades. Allergy risk factors and cow's milk allergen sensitization ... -
Pengaruh Kitosan terhadap Gambaran Histopatologis Testis, Kuantitas dan Kualitas Sperma Tikus Putih Jantan (Rattus sp.) setelah Dipapari Plumbum Asetat
(Universitas Sumatera Utara, 2015)Background: Plumbum as one of the contaminants can affect people's health such as reproductive health, so that should be the prevention of and protection against interference. Objective: Looking at the effect of chitosan ... -
Adenomatous Polyposis Coli, Mismatch Repair dan Instabilitas Mikrosatelit Kanker Kolorektal Berdasarkan Perbedaan Lokasi antara Kolon Proksimal, Distal dan Rektum
(Universitas Sumatera Utara, 2013)Background: In Western countries most of colorectal cancer (CRC) cases are found in the colon (proximal and distal) rather than in the rectum. Each location can result in defferent clinical, pathological and molecular ... -
Pengaruh Ekstrak Etanol Buah Andaliman terhadap Kadar Mda, Ekspresi BDNF, VEGF, p16INK4a dan Fungsi Memori Hipokampus pada Tikus Model Penuaan
(Universitas Sumatera Utara, 2022)Background: The increasing number of elderly population is currently an important issue for the world. Indonesia is also experiencing an increase in population. Physiological aging and aging due to oxidative stress in ... -
Asosiasi antara Alel Gen HLA-DRB1 dan HLA-DQB1 dengan Kerentanan Timbulnya Karsinoma Nasofaring pada Suku Batak
(Universitas Sumatera Utara, 2007)HIA gene is suspected to be have a role in the development of nasopharyngeal carcinoma (NPC). To assess the relation between HLA- DRBl dan HLA-DQB1 alleles with NPC among the Batak people, this case- control study was ... -
Penilaian Reperfusi Myocardial Perfusion Contraction Grade (MPCG) dan Myocardial Blush Grade (MBG) Pasca Intervensi Koroner Perkutan Primer (IKPP) pada Penderita Infark Miokard Akut- Elevast ST Segmen
(Universitas Sumatera Utara, 2014)Backgrounds : Assesment of myocardial reperfusion after primary Percutaneous Coronary lntervention (pPCI) for patients acute myocardial infarction is not only restoration of macrovascular epicardial coronary artery (TlMl ... -
Pengaruh Pemberian Enteral Ekstrak Cucumis Melo L.C Gliadin sebagai Profilaksis Antioxidan pada Tikus Wistar Model Sepsis dengan Pemeriksaan Kadar SOD, MDA, TNF ALFA dan Laktat Serum
(Universitas Sumatera Utara, 2022)Background: Sepsis is one of the most common causes of death in intensive care units. Sepsis is an excessive stimulus response from an organism. In sepsis there is an inflammatory response, several mediators such as cytokines ... -
Rendahnya Ekspresi Fibroblast Growth Factor Receptor-3 (FGFR3), Tingginya Ekspresi p53 dan Tingginya Ekspresi Hypoxia Inducible Factor-1a (HIF-1a) sebagai Faktor Prediktor Invasi Otot pada Kanker Kandung Kemih
(Universitas Sumatera Utara, 2017)Introduction: The main risks in patients diagnosed with non muscle invasive bladder cancer (NMIBC) are recurrence, progression of muscle invasiveness (MIBC), or metastasis. Biological markers FGFR3, p53, and HIF-1a. are ... -
Peranan Polimorfisme P213S L-Selektin dan Profil Makrofag (M1,M2) pada Kasus Endometriosis
(Universitas Sumatera Utara, 2014)Objective : To determine the presence of a L-selectin P213S polymorphisme in association with the pathogenesis of endometriosis. Design: Comparative analytical study using a case-control design. Setting : Department of ... -
Profil Sekresi Sitokin oleh Th1/Th2 pada Penderita Stomatitis Aftosa Rekuren Terkait Stres
(Universitas Sumatera Utara, 2012)Oral ulcer called Recurrent Aphthous Stomatitis (RAS) has always been a complaint of patients who come to seek treatment. Multifactorial etislo-gi sf the disease, so the diagnssis is only base on histsry and eliniea.! ... -
Hubungan Polimorfisme Gen Reseptor Vitamin D (Taql dan Bsml), Gaya Hidup, dan Lemak Tubuh dengan Kadar 25(OH) D Serum pada Perempuan
(Universitas Sumatera Utara, 2013)Background: Many studies show that low circulating 25(OH)D serum level may increase risk of morbidity and mortality, especially in women and vitamin D deficiency are considered new markers for metabolic disease- Objective: ... -
Pengaruh Kombinasi Interval Training Tipe Lambat dan Ekstrak Etanol Sarang Semut (Myrmecodia Pendans) terhadap Ekspresi Superoxide Dismutase, Kadar P-Selectin dan Jumlah Sel Busa pada Tikus Galur Wistar Model Diabetes Melitus Tipe-2
(Universitas Sumatera Utara, 2022)Background. Macrovascular complications in diabetes mellitus (DM) are the most common cause of death in DM patients. The accumulation of free radicals induced by hyperglycemia causes endothelial dysfunction characterized ... -
Peran Doksisiklin Sebagai MMP-1 Inhibitor pada Infeksi Spondilitis Tuberkulosis Model Kelinci
(Universitas Sumatera Utara, 2022)Introduction It is estimated that approximately one third of the world's population is infected with the bacterium Mycobacterium tuberculosis, which is the cause of tuberculosis (TB) infection, although only 5% of those ... -
Hubungan Polimorfisme M98K dan T34T dari Optineurin (OPTN) dengan Kejadian Glaukoma Sudut Terbuka Primer
(Universitas Sumatera Utara, 2013)BACKGROUND: Glaucoma is the leading cause of irreversible blindness in the world. Recent evidence indicates genetics susceptibility plays a role in primary open-angle glaucoma (POAG). The optineurin gene (OPTN) is the ... -
Korelasi Nilai Skor Tes Gambar Kompleks Rey-Osterrieth dengan Luas dan Letak Lesi Infark di Otak pada Penderita Stroke Iskemik Hemisfer Kanan
(Universitas Sumatera Utara, 2002)Background : Stroke is one of the main causes of human brain disturbances at the peak of productive ages and is placed at rank number two as the death cause after heart diseases in most countries. With CT Scan, diagnosis ... -
Korelasi Ekspresi Reseptor Histamin1 (H1) dan Vascular Endothelial Growth Factor (VEGF) sebagai Faktor Risiko Konka Hipertropi yang Disebabkan oleh Rinitis Alergi
(Universitas Sumatera Utara, 2014)Although hypertropic concha does not threaten our life, it disturbs quality of life and becomes financial burden of the suferrer. Hypertropic concha is often found in patients with allergic rhinitis and non allergic ...
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