Master Theses (Biomedical Science)
Master Theses (Biomedical Science)
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Hubungan antara Polimorfisme Gen SIRT1 (rs12778366 dan rs3758391) dan Kadar SIRT1 Serum dengan Kerentanan Fisik pada Lansia dengan Multimorbiditas
(Universitas Sumatera Utara, 2025)Latar Belakang: Frailty merupakan sindrom klinis yang ditandai dengan menurunnya cadangan fisiologis tubuh dan meningkatnya kerentanan terhadap dampak buruk kesehatan, terutama pada lanjut usia dengan kondisi multimorbiditas. ... -
Uji Efektivitas Ekstrak Buah Andaliman (Zanthoxylum Acanthopodium DC) Terhadap Bakteri Methicillin-Susceptible Staphylococcus aureus (MSSA) dan Methicillin-Resistant Staphylococcus aureus (MRSA)
(Universitas Sumatera Utara, 2025)Antimicrobial resistance, particularly Methicillin-Resistant Staphylococcus aureus (MRSA), poses a major challenge in modern healthcare due to its resistance to various antibiotics. Andaliman fruit (Zanthoxylum ... -
Pengaruh Ekstrak Propolis Terhadap Malondialdehid dan Interleukin-6 serta Histopatologi Usus pada Tikus Model Sepsis yang Diinduksi Injeksi Feses Intraperitoneal
(Universitas Sumatera Utara, 2025)Background: Dysbiosis contributes to the development of inflammatory diseases through the destruction of intestinal barrier or leaky gut, allowing pathogens to invade the intestines and triggering the release of proinflammatory ... -
Efek Kombinasi Ekstrak Etanol Batang Serai (Cymbopogon citratus) dan Latihan Slow Interval Training Terhadap Berat Badan, Lingkar Perut, Massa Lemak Perut dan Ekspresi Gen Obrb Leptin Pada Tikus Galur Wistar (Rattus norvegicus) Jantan Model Obesitas
(Universitas Sumatera Utara, 2025)Background: Obesity is a global health issue characterized by increased body fat and leptin resistance, which plays a crucial role in regulating appetite and energy metabolism. Objective: This study aimed to analyze the ... -
Pengaruh Sport Massage dengan Minyak Jahe Merah terhadap Penurunan Nyeri Otot dan Creatine Kinase Akibat Delayed Onset Muscle Soreness (DOMS) pada Atlet Muay Thai di Kota Medan
(Universitas Sumatera Utara, 2025)Background: Delayed onset muscle soreness (DOMS) is a delayed muscle pain caused by micro-damage to the muscles after high-intensity, eccentric sports activities or different types of exercise from before. Micro-damage to ... -
Efek Ekstrak Etanol Buah Nipah (Nypa fruticans) Terhadap Kadar PI3K Dan TNF-α pada Tikus Putih Galur Wistar Jantan Model Obesitas
(Universitas Sumatera Utara, 2025)Background: Obesity is a metabolic disorder characterized by excess fat accumulation and chronic inflammation, leading to increased risk of insulin resistance and metabolic complications. Natural products such as Nypa ... -
Pengaruh Latihan Pilates Terhadap Health Related Physical Fitness, Kapasitas Paru dan Immonuglobulin-A pada Subjek Tidak Terlatih
(Universitas Sumatera Utara, 2025)Exercise is a structured form of physical activity performed with the aim of improving fitness, health, or physical performance. Physical activity includes any form of body movement that involves muscle contraction and ... -
Efek Antiinflamasi dan Nefroprotektif Ekstrak Propolis pada Tikus yang Diinduksi dengan Monosodium Glutamate (MSG)
(Universitas Sumatera Utara, 2025)Background: Chronic kidney disease is a global health problem, affecting more than 800 million people and increasing every year. The disease can be triggered by organ inflammation due to excessive use of certain substances ... -
Pengembangan DNA Ladder Ukuran Fragmen 100-10.000 bp dengan Metode PCR dari Genom Escherichia coli ATCC 25922
(Universitas Sumatera Utara, 2025)Reference standards are very important in scientific investigations for producing accurate, reproducible, and quantitative data. One key reference standard in biomolecular laboratories is DNA ladder, which comprises a range ... -
Hubungan Polimorfismegen Growth Hormone 1 rs2665802 Terhadap Tinggi Badan dan Kadar Somatotropin Darah pada Perempuan Suku Nias
(Universitas Sumatera Utara, 2025)Background: Height is an important indicator of human growth influenced by genetic and hormonal factors. The Growth Hormone 1 (GH1) gene regulates the production of somatotropin, a key growth hormone. The GH1 rs2665802 ... -
Efek Kombinasi Ekstrak Daun Serai (Cymbopogon Citratus) dan Latihan Fisik Terhadap Kadar Profil Lipid pada Tikus Galur Wistar (Rattus Norvegicus) Jantan Model Hiperlipidemia
(Universitas Sumatera Utara, 2025)Background: Hyperlipidemia is a major risk factor for cardiovascular disease, with a high prevalence in Indonesia reaching 69.9%. Non-pharmacological approaches such as physical exercise and herbal therapy are increasingly ... -
Pengaruh Manual Traksi Fisioterapi terhadap Knee Injury and Osteoarthritis Outcome Score dan Kadar Interleukin-6 Serum pada Pasien Osteoartritis Lutut
(Universitas Sumatera Utara, 2025)Background: Knee osteoarthritis (OA) is the most common degenerative joint disease with a high prevalence worldwide. Knee OA causes pain, joint stiffness, muscle weakness, and decreased functional activity, significantly ... -
Pengaruh Ekstrak Jamur Tiram Putih (Pleurotus ostreatus) terhadap Kualitas Sperma Tikus Wistar Putih Jantan (Rattus norvegicus) yang Diinduksi oleh Cyclophosphamide
(Universitas Sumatera Utara, 2024)Infertility is still a scourge for couples, especially men. Treatment options for infertility are still limited, so further comprehensive research efforts are needed. White oyster mushrooms are known to have ingredients ... -
Pengaruh Pemberian Ekstrak Daun Pirdot (Saurauia vulcani Korth.) terhadap Ekspresi Gen Sod1, Sod2 dan Perbaikan Lokomotor pada Drosophila melanogaster Model Hiperglikemia
(Universitas Sumatera Utara, 2024)High sugar diet is often associated with increased blood sugar (hyperglycemia). Hyperglycemia that occurs continuously can trigger an imbalance between increased ROS production through mitochondrial dysfunction and reduced ... -
Pengaruh Pemberian Ekstrak Etanol Daun Pirdot (Saurauia vulcani Korth.) terhadap Kadar Glukosa, Ekspresi Gen TotA, Dpt, dan Perkembangan pada Drosophila melanogaster Model Hiperglikemia
(Universitas Sumatera Utara, 2024)Hyperglycemia is a condition where blood sugar (glucose) levels exceed normal limits. Hyperglycemia is a global health problem that can be an early symptom of diabetes mellitus (DM). High blood glucose levels can impair ... -
Efek Katekin Daun Gambir (Uncaria gambir Roxb) terhadap Kadar Malondialdehid Serum dan Ekspresi Gen Superoksida Dismutase 2 (Sod2) pada Hipokampus Mencit Betina Model Penuaan
(Universitas Sumatera Utara, 2020)Aging is a process of free radicals accumulation which form in normal metabolism and results in cell damage. Increasing age causes cell mutations and degenerative diseases. Malondialdehyde (MDA) is a product of lipid ... -
Pengaruh Pemberian Ekstrak Daun Pirdot (Saurauia vulcani Korth.) terhadap Ekspresi Gen Dilp 2, Dilp 5, Bobot dan Lokomotor Larva Drosophila melanogaster Model Hiperglikemia
(Universitas Sumatera Utara, 2024)Hyperglycemia is a medical condition caused by elevated blood glucose levels often associated with diabetes mellitus (DM). Pirdot leaf extract (Saurauia vulcani Korth.) is traditionally known for its potential antihyperglycemic ... -
Efektivitas Ekstrak Air Daun Binahong (Anredera cordifolia (Ten)) dalam Menurunkan Inflamasi Gingiva pada Pasien Diabetes Melitus Tipe II
(Universitas Sumatera Utara, 2024)Indonesia is among the top 10 countries with the highest prevalence of diabetes mellitus type II with the sharpest increase. Most of it can not diagnosed until have symptoms related to severe hyperglycemia. The most ... -
Profil Genetik Polimorfisme CYP3A4*4, *18B, dan *22 pada Kelompok Etnis Batak Toba, Melayu, dan Nias
(Universitas Sumatera Utara, 2024)CYP3A4 is an important isoform of the CYP450 enzyme that participates in drug metabolism, as well as the major CYP3A isoform in the human liver and small intestine. However, CYP3A4 shows the greatest inter-individual ... -
Pengaruh Teknik Traksi Manual Fisioterapi Terhadap Kadar Telopeptida Cross-Link C-Terminal Kolagen Tipe II (CTX-II) Dan Western Ontario And Mcmaster University Oa Index (WOMAC) Pada Pasien Osteoarthritis Lutut
(2025)Knee osteoarthritis (OA) is a degenerative joint disease characterized by cartilage damage, leading to chronic pain, stiffness, and functional limitations. This study aimed to analyze the effects of manual traction ...
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