Browsing Master Theses (Biomedical Science) by Issue Date
Now showing items 1-20 of 211
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Pengaruh Teknik Traksi Manual Fisioterapi Terhadap Kadar Telopeptida Cross-Link C-Terminal Kolagen Tipe II (CTX-II) Dan Western Ontario And Mcmaster University Oa Index (WOMAC) Pada Pasien Osteoarthritis Lutut
(2025)Knee osteoarthritis (OA) is a degenerative joint disease characterized by cartilage damage, leading to chronic pain, stiffness, and functional limitations. This study aimed to analyze the effects of manual traction ... -
Pengaruh Kombinasi Nuget Ikan Lemuru (Sardinella lemuru) dan Tepung Biji Durian (Durio zibethinus) terhadap Nilai Z Score dan Kadar Serum BDNF pada Anak Stunting
(Universitas Sumatera Utara, 2024)Nuget Combination of Lemuru Fish (Sardinella lemuru) and Durian Seed Flour (Durio zibethinus) or Nugilempudu is proven to reduce stunting index levels, but the mechanism is still unclear.This study aims to determine the ... -
Efektifitas Suplementasi Minyak Kelapa Sawitmerah terhadap Penyakit Parkinson melalui Gambaran Motorik, Histologi dan Kadar Mda pada Tikus Putih Model Parkinson
(Universitas Sumatera Utara, 2024)Parkinson's is a neurological disease that is rapidly increasing to surpass Alzheimer's disease. Parkinson's disease causes a decrease in the number of dopaminergic neurons which can lead to disturbances in attention, ... -
Profil Genetik Polimorfisme CYP3A4*4, *18B, dan *22 pada Kelompok Etnis Batak Toba, Melayu, dan Nias
(Universitas Sumatera Utara, 2024)CYP3A4 is an important isoform of the CYP450 enzyme that participates in drug metabolism, as well as the major CYP3A isoform in the human liver and small intestine. However, CYP3A4 shows the greatest inter-individual ... -
Efektivitas Ekstrak Air Daun Binahong (Anredera cordifolia (Ten)) dalam Menurunkan Inflamasi Gingiva pada Pasien Diabetes Melitus Tipe II
(Universitas Sumatera Utara, 2024)Indonesia is among the top 10 countries with the highest prevalence of diabetes mellitus type II with the sharpest increase. Most of it can not diagnosed until have symptoms related to severe hyperglycemia. The most ... -
Pengaruh Pemberian Ekstrak Daun Pirdot (Saurauia vulcani Korth.) terhadap Ekspresi Gen Dilp 2, Dilp 5, Bobot dan Lokomotor Larva Drosophila melanogaster Model Hiperglikemia
(Universitas Sumatera Utara, 2024)Hyperglycemia is a medical condition caused by elevated blood glucose levels often associated with diabetes mellitus (DM). Pirdot leaf extract (Saurauia vulcani Korth.) is traditionally known for its potential antihyperglycemic ... -
Pengaruh Pemberian Ekstrak Etanol Daun Pirdot (Saurauia vulcani Korth.) terhadap Kadar Glukosa, Ekspresi Gen TotA, Dpt, dan Perkembangan pada Drosophila melanogaster Model Hiperglikemia
(Universitas Sumatera Utara, 2024)Hyperglycemia is a condition where blood sugar (glucose) levels exceed normal limits. Hyperglycemia is a global health problem that can be an early symptom of diabetes mellitus (DM). High blood glucose levels can impair ... -
Pengaruh Pemberian Ekstrak Daun Pirdot (Saurauia vulcani Korth.) terhadap Ekspresi Gen Sod1, Sod2 dan Perbaikan Lokomotor pada Drosophila melanogaster Model Hiperglikemia
(Universitas Sumatera Utara, 2024)High sugar diet is often associated with increased blood sugar (hyperglycemia). Hyperglycemia that occurs continuously can trigger an imbalance between increased ROS production through mitochondrial dysfunction and reduced ... -
Pengaruh Ekstrak Jamur Tiram Putih (Pleurotus ostreatus) terhadap Kualitas Sperma Tikus Wistar Putih Jantan (Rattus norvegicus) yang Diinduksi oleh Cyclophosphamide
(Universitas Sumatera Utara, 2024)Infertility is still a scourge for couples, especially men. Treatment options for infertility are still limited, so further comprehensive research efforts are needed. White oyster mushrooms are known to have ingredients ... -
Efek Ekstrak Channa Striata (Ikan Gabus) terhadap Kadar Serotonin yang Dihubungkan dengan Fungsi Kognitif pada Lansia di Puskesmas Kota Matsum Medan Area Kota Medan
(Universitas Sumatera Utara, 2023)Serotonin (5-HT) is a neurotransmitter that has been shown to be involved in various brain functions including cognitive function. With increasing age, the synthesis of serotonin decreases. Low serotonin levels are associated ... -
Efek Kombinasi Ekstrak Pegagan (Centella asiatica) dan Ikan Gabus (Channa striata) terhadap Fungsi Kognitif dan Kadar Mda (Malondialdehyde) Tikus Model Penuaan yang Diinduksi D-Galaktosa
(Universitas Sumatera Utara, 2023)The prevalence of cognitive impairment in older adults are estimated at 5-7%. In aging there is an increase in oxidative stress which causes damage to the structure and function of neurons. Dysfunction neuron cells can be ... -
Efek Pemberian Ekstrak Etanol Kulit Melinjo (Gnetum gnemon) terhadap Ekspresi Gen URAT1 dan GLUT9 pada Tikus Wistar Model Hiperurisemia
(Universitas Sumatera Utara, 2023)Hyperuricemia can occur because uric acid levels in the blood exceed normal limits. Where uric acid itself is the end product of purine metabolism in the body. Prolonged hyperuricemia will lead to gout, the consequences ... -
Efek Imunomodulator Ekstrak Etanol Daun Pirdot (Saurauia vulcani Korth ) terhadap Profil Sel T CD4+ Hepar dan Kadar IL 2 Serum pada Tikus Galur Wistar yang Diinduksi Salmonella typhimurium
(Universitas Sumatera Utara, 2023)Salmonella typhimurium is an intracellular bacteria that can affect the immune system so that an immunomodulator is needed to modulate the function and activity of the immune system. CD4+ and IL2 T cells are one of the ... -
Polimorfisme Gen Leptin -2548G>A(RS7799039) dan Gen Ghrelin LEU72MET(RS696217) pada Penderita DM Tipe 2 di Kota Medan
(Universitas Sumatera Utara, 2023)Diabetes Mellitus type 2 is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion and insulin action or both which can be caused by environmental influences in the form of lifestyle, ... -
Efek Pemberian Ekstrak Etanol Daun Talas Padang (Colocasia Gigantea) terhadap Ekspresi AMPK a1 Otot Skeletal dan PEPT1 Usus Halus pada Tikus Galur Wistar Model Malnutrisi
(Universitas Sumatera Utara, 2023)Stunting is a condition of lack of nutrition in the long term which can be caused molecularly by malnutrition. Malnutrition can be caused by a lack of energy or protein which results in a decrease in muscle mass due to ... -
Efek Antiinflamasi Ekstrak Ikan Gabus (Channa Striata) pada Tikus Model Pneumonia yang di Induksi dengan LPS E. Coli Secara Intratrakeal
(Universitas Sumatera Utara, 2023)Nosocomial pneumonia is an infection of the lungs that occurs after being treated in a hospital. Pneumonia is generally caused by Escherichia coli which causes acute inflammation and respiratory distress. The interaction ... -
Pengaruh Suhu dan Konsentrasi EDTA terhadap Inaktivasi DNase I untuk Preservasi DNA Asal Saliva
(Universitas Sumatera Utara, 2023)Background: Deoxyribonuclease I (DNase I) catalyzes the endonucleolytic cleavage of double stranded DNA into phosphodinucleotides and phosphooligonucleotides. DNase inactivation is influenced by EDTA, pH, and temperature. ... -
Efek Pemberian Ekstrak Etanol Daun Pirdot (saurauia vulcani korth.) terhadap Cellular Senescence pada Jaringan Adiposa Putih Tikus Galur Wistar yang Diberi Diet Tinggi Lemak
(Universitas Sumatera Utara, 2023)Increasing body fat can induce formation of reactive oxygen species (ROS) through excessive production of NADH and FADH2. High level of ROS may cause DNA damage and then disrupts the cell cycle (cellular senescence). Adipose ... -
Efek Pemberian Ekstrak Etanol Kulit Melinjo (Gnetum gnemon) terhadap Ekspresi Alt1 dan Hgf Hepar Tikus Galur Wistar Model Hiperurisemia
(Universitas Sumatera Utara, 2023)Hyperuricemia can induce a dysfunctional exchange of sodium and calcium in mitochondria which will lead to the production of reactive oxygen species (ROS). ROS plays a role in aging, DNA damage, oxidation, production of ... -
Hubungan Polimorfisme (RS2273773) pada Gen SIRT1 dengan Kadar SIRT1 Plasma dan Kelemahan (FRAILTY) pada Orang Lanjut Usia
(2023)Background. Frailty is defined as a syndrome of age-related physical decline characterized by significant vulnerability to health issues. The diagnosis of frailty is established based on three or more of five criteria, ...