Master Theses (Biomedical Science)

Efek Pemberian Ekstrak Etanol Kulit Melinjo (Gnetum gnemon) terhadap Ekspresi Alt1 dan Hgf Hepar Tikus Galur Wistar Model Hiperurisemia

Mentari, Cindy (Universitas Sumatera Utara, 2023)

Hyperuricemia can induce a dysfunctional exchange of sodium and calcium in mitochondria which will lead to the production of reactive oxygen species (ROS). ROS plays a role in aging, DNA damage, oxidation, production of ...

Efek Pemberian Ekstrak Etanol Daun Pirdot (saurauia vulcani korth.) terhadap Cellular Senescence pada Jaringan Adiposa Putih Tikus Galur Wistar yang Diberi Diet Tinggi Lemak

Sitepu, Nova Eininta (Universitas Sumatera Utara, 2023)

Increasing body fat can induce formation of reactive oxygen species (ROS) through excessive production of NADH and FADH2. High level of ROS may cause DNA damage and then disrupts the cell cycle (cellular senescence). Adipose ...

Hubungan Polimorfisme Glutathion S Transferase P-1 (GSTPl) dengan Insidensi dan Derajat Mielosupresi pada Pasien Kanker Payudara yang Diterapi dengan Regimen Mengandung Siklofosfamid

Hasni, Dita (Universitas Sumatera Utara, 2014)

As one of most important breast cancer treatments, chemotherapy often complicated by hematopoetic toxicity. Today, Genetic polymorphism has been linked to inter individual differences in terms of toxic severity of various ...

Efek Pemberian Ekstrak Etanol Daun Talas Padang (Colocasia Gigantea) terhadap Ekspresi AMPK a1 Otot Skeletal dan PEPT1 Usus Halus pada Tikus Galur Wistar Model Malnutrisi

Husna, Adlina Karimina Nurul (Universitas Sumatera Utara, 2023)

Stunting is a condition of lack of nutrition in the long term which can be caused molecularly by malnutrition. Malnutrition can be caused by a lack of energy or protein which results in a decrease in muscle mass due to ...

Efek Imunomodulator Ekstrak Etanol Daun Pirdot (Saurauia vulcani Korth ) terhadap Profil Sel T CD4+ Hepar dan Kadar IL 2 Serum pada Tikus Galur Wistar yang Diinduksi Salmonella typhimurium

Haslinda, Haslinda (Universitas Sumatera Utara, 2023)

Salmonella typhimurium is an intracellular bacteria that can affect the immune system so that an immunomodulator is needed to modulate the function and activity of the immune system. CD4+ and IL2 T cells are one of the ...

Efek Antiinflamasi Ekstrak Ikan Gabus (Channa Striata) pada Tikus Model Pneumonia yang di Induksi dengan LPS E. Coli Secara Intratrakeal

Putri, Yulia (Universitas Sumatera Utara, 2023)

Nosocomial pneumonia is an infection of the lungs that occurs after being treated in a hospital. Pneumonia is generally caused by Escherichia coli which causes acute inflammation and respiratory distress. The interaction ...

Pengaruh Suhu dan Konsentrasi EDTA terhadap Inaktivasi DNase I untuk Preservasi DNA Asal Saliva

Sulviani, Nurul (Universitas Sumatera Utara, 2023)

Background: Deoxyribonuclease I (DNase I) catalyzes the endonucleolytic cleavage of double stranded DNA into phosphodinucleotides and phosphooligonucleotides. DNase inactivation is influenced by EDTA, pH, and temperature. ...

Polimorfisme Gen Leptin -2548G>A(RS7799039) dan Gen Ghrelin LEU72MET(RS696217) pada Penderita DM Tipe 2 di Kota Medan

Lewis, Edwin (Universitas Sumatera Utara, 2023)

Diabetes Mellitus type 2 is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion and insulin action or both which can be caused by environmental influences in the form of lifestyle, ...

Efek Pemberian Ekstrak Etanol Kulit Melinjo (Gnetum gnemon) terhadap Ekspresi Gen URAT1 dan GLUT9 pada Tikus Wistar Model Hiperurisemia

Sofyan, Nurul Amalia (Universitas Sumatera Utara, 2023)

Hyperuricemia can occur because uric acid levels in the blood exceed normal limits. Where uric acid itself is the end product of purine metabolism in the body. Prolonged hyperuricemia will lead to gout, the consequences ...

Efek Kombinasi Ekstrak Pegagan (Centella asiatica) dan Ikan Gabus (Channa striata) terhadap Fungsi Kognitif dan Kadar Mda (Malondialdehyde) Tikus Model Penuaan yang Diinduksi D-Galaktosa

Siregar, Sarah Rahmayani (Universitas Sumatera Utara, 2023)

The prevalence of cognitive impairment in older adults are estimated at 5-7%. In aging there is an increase in oxidative stress which causes damage to the structure and function of neurons. Dysfunction neuron cells can be ...

Efek Ekstrak Channa Striata (Ikan Gabus) terhadap Kadar Serotonin yang Dihubungkan dengan Fungsi Kognitif pada Lansia di Puskesmas Kota Matsum Medan Area Kota Medan

Pasaribu, Rifqi Hamdani (Universitas Sumatera Utara, 2023)

Serotonin (5-HT) is a neurotransmitter that has been shown to be involved in various brain functions including cognitive function. With increasing age, the synthesis of serotonin decreases. Low serotonin levels are associated ...

Korelasi Retinol Binding Protein 4 (RBP4) dengan Kadar Trigliserida dan APO B100 pada Obesitas Sentral

Oktaria, Selly (Universitas Sumatera Utara, 2016)

Background : Obesity has become an epidemic both in developed and developing countries. Central obesity is considered as a risk factor which is strongly correlated with several chronic disease. Central obesity correlated ...

Pengaruh Kebisingan terhadap Tekanan Darah Pekerja Laki Laki Masa Dewasa Dini di Industri Karet Deli Medan

Lubis, Wilda Hafny (Universitas Sumatera Utara, 1999)

Telah dilakukan penelitian pengaruh kebisingan terhadap tekanan darah pekerja laki - laki masa dewasa dini di Industri Karet Deli Medan, yang dilakukan secara cross sectional respondennya adalah 78 pekerja laki laki yang ...

Efek Jamur Tiram Putih (Pleurotus ostreatus) terhadap Perlemakan Hati Non-Alkoholik pada Tikus Jantan Galur Wistar yang Diberi Minyak Jelantah

S, Saharnauli J V (Universitas Sumatera Utara, 2014)

Recycling cooking oil for deep frying makes the transformation of certain unsaturated fatty acid from cis to trans configuration. There is a direct effect of trans fatty acid on Nonalcoholic Fatty Liver Disease (NAFLD). ...

Hubungan Polimorfisme Glutathion S- Transferase P-1 (GSTP1) dengan Insidensi dan Derajat Mielosupresi pada Pasien Kanker Payudara yang Diterapi dengan Regimen Mengandung Siklofosfamid

Hasni, Dita (Universitas Sumatera Utara, 2014)

As one of mast intportant breast c(mcer treatments, chemotherapy ofien complicated by hematopoettc toxictty. Toduy, Genetic polymorphism has been linlred to inter individual dffirences in terms af toric severtty of various ...

Gambaran Histopatologi Ketebalan Epitel Tubulus Seminiferus Testis serta Kualitas dan Kuantitas Sel Sperma Tikus (Rattus novergicus Strain Wistar) Hiperkolesterolemia yang Diberi Vitamin C

Ismail, Wan Muhammad (Universitas Sumatera Utara, 2013)

Hypercholesterolemia can causes the abnormalities of the male reproductive function , achieved increase of oxygen radicals and lipid peroxidation production in different tissue, and inducing oxidative stress. The results ...

Pengaruh Pemberian Vitamin E terhadap Gambaran Histologi dan Kadar SGOT/SGPT Hati Mencit (Mus musculus L.) Jantan yang Dipapari Tuak

Manurung, Kesaktian (Universitas Sumatera Utara, 2011)

Vitamin E is one of the vitamins which are soluble in fat and plays a role as an antioxidant and even can keep the destructive biological membrane action from free radical and keep unsaturated fatty acids from phospolipids ...