Master Theses (Biomedical Science)
Master Theses (Biomedical Science)
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Efektifitas Suplementasi Minyak Kelapa Sawitmerah terhadap Penyakit Parkinson melalui Gambaran Motorik, Histologi dan Kadar Mda pada Tikus Putih Model Parkinson
(Universitas Sumatera Utara, 2024)Parkinson's is a neurological disease that is rapidly increasing to surpass Alzheimer's disease. Parkinson's disease causes a decrease in the number of dopaminergic neurons which can lead to disturbances in attention, ... -
Perbedaan Kadar VEGF (Vascular Endothelial Growth Factor) dan IGF-1 (Insulin like Growth Factor-1) pada Pasien Diabetes Melitus Tipe 2 yang Terkontrol dan Tidak Terkontrol di Puskesmas Padang Bulan Kota Medan
(Universitas Sumatera Utara, 2023)Background: Diabetes Mellitus is a metabolic disorder characterized by an increase in blood sugar due to decreased insulin secretion by pancreatic beta cells or impaired insulin function (insulin resistance) which can ... -
Deteksi Gen TOP2A, MC4R, dan NOTCH3 dengan Menggunakan Metode Long PCR pada Saliva Manusia yang Sudah Dipreservasi
(Universitas Sumatera Utara, 2023)Background: Technological developments enabled modification of techniques in the field of molecular biology. DNA can be isolated from various biological sources such as blood, saliva, buccal swab, sperm, or biopsy tissue. ... -
Pengaruh Kombinasi Nuget Ikan Lemuru (Sardinella lemuru) dan Tepung Biji Durian (Durio zibethinus) terhadap Nilai Z Score dan Kadar Serum BDNF pada Anak Stunting
(Universitas Sumatera Utara, 2024)Nuget Combination of Lemuru Fish (Sardinella lemuru) and Durian Seed Flour (Durio zibethinus) or Nugilempudu is proven to reduce stunting index levels, but the mechanism is still unclear.This study aims to determine the ... -
Deteksi Gen ESRl, EGFR, PTK2, JAK2, dan FGFR2 pada DNA Preservasi Asal Saliva Manusia yang Diberi Kombinasi Antimikroba dan Penghambat DNase
(Universitas Sumatera Utara, 2023)Background: Genomic DNA preservation protects and stores DNA for a long time in storage containers so that DNA can be used at any time. DNA serves as a carrier of genetic information from one generation to another. DNA ... -
Efek Curcuma longa L. terhadap Titer Antibodi dan Berat Badan Domba Pasca Vaksinasi Penyakit Mulut dan Kuku
(Universitas Sumatera Utara, 2023)Foot and mouth disease (FMD) is an acute and highly contagious viral infectious disease in animals with even/split hooves and some wild animals. The most important factor in controlling FMD is vaccination. The disadvantages ... -
Efek Kombinasi Ekstrak Pegagan dan Ikan Gabus terhadap Kadar MDA Serum, Ekpresi Gen VEGF pada Jaringan Otak dan Fungsi Memori Spasial pada Tikus yang Diinduksi D-Galaktosa
(Universitas Sumatera Utara, 2023)Background: During the aging process, the body's ability to cope with the effects of free radicals such as reactive oxygen species decreases. The process of membrane lipid oxidation due to free radicals produces lipid ... -
Efek Antiinflamasi Ekstrak Sambiloto pada Tikus Model Pneumonia yang di Induksi dengan Lipopolisakarida Intratrakeal
(Universitas Sumatera Utara, 2023)Pneumonia is a common disease in developing countries that affects around 450 million people every year. The most common cause of pneumonia is gram-negative bacilli, which have endotoxins that can be released into the ... -
Hubungan Polimorfisme RS7069102 pada Gen SIRT 1 dengan Kadar SIRT 1 Plasma dan Kelemahan(FRAILTY) pada Orang Lanjut Usia
(Universitas Sumatera Utara, 2023)The number of elderly people is increasing every year. Aging in the elderly will be followed by frailty which can result in cumulative changes, ultimately resulting in chronic disease. To prevent the occurrence of chronic ... -
Hubungan Polimorfisme (RS2273773) pada Gen SIRT1 dengan Kadar SIRT1 Plasma dan Kelemahan (FRAILTY) pada Orang Lanjut Usia
(2023)Background. Frailty is defined as a syndrome of age-related physical decline characterized by significant vulnerability to health issues. The diagnosis of frailty is established based on three or more of five criteria, ... -
Hubungan Polimorfisme RS7895833 pada Gen SIRT1 dengan Kadar SIRT1 Plasma dan Kelemahan (FRAILTY) pada Pralansia dan Lansia
(Universitas Sumatera Utara, 2023)The number of elderly people increases every year. Increasing age in the elderly is followed by frailty which causes changes in the body's physiology and ultimately can result in the emergence of various diseases that can ... -
Asosiasi Polimorfisme Gen BACE1 (rs638405) dengan Kadar BACE1 dan Fungsi Kognitif pada Lansia dengan Diabetes Tipe 2 di Kota Medan
(Universitas Sumatera Utara, 2023)Background: Cognitive impairment has an impact on functional abilities and care needs in the elderly. The BACE1 gene polymorphism on the G allele (rs638405) is a risk marker for Alzheimer's disease in Asian and Caucasian ... -
Efek Pemberian Ekstrak Etanol Kulit Melinjo (Gnetum gnemon) terhadap Ekspresi Alt1 dan Hgf Hepar Tikus Galur Wistar Model Hiperurisemia
(Universitas Sumatera Utara, 2023)Hyperuricemia can induce a dysfunctional exchange of sodium and calcium in mitochondria which will lead to the production of reactive oxygen species (ROS). ROS plays a role in aging, DNA damage, oxidation, production of ... -
Efek Pemberian Ekstrak Etanol Daun Pirdot (saurauia vulcani korth.) terhadap Cellular Senescence pada Jaringan Adiposa Putih Tikus Galur Wistar yang Diberi Diet Tinggi Lemak
(Universitas Sumatera Utara, 2023)Increasing body fat can induce formation of reactive oxygen species (ROS) through excessive production of NADH and FADH2. High level of ROS may cause DNA damage and then disrupts the cell cycle (cellular senescence). Adipose ... -
Hubungan Polimorfisme Glutathion S Transferase P-1 (GSTPl) dengan Insidensi dan Derajat Mielosupresi pada Pasien Kanker Payudara yang Diterapi dengan Regimen Mengandung Siklofosfamid
(Universitas Sumatera Utara, 2014)As one of most important breast cancer treatments, chemotherapy often complicated by hematopoetic toxicity. Today, Genetic polymorphism has been linked to inter individual differences in terms of toxic severity of various ... -
Efek Pemberian Ekstrak Etanol Daun Talas Padang (Colocasia Gigantea) terhadap Ekspresi AMPK a1 Otot Skeletal dan PEPT1 Usus Halus pada Tikus Galur Wistar Model Malnutrisi
(Universitas Sumatera Utara, 2023)Stunting is a condition of lack of nutrition in the long term which can be caused molecularly by malnutrition. Malnutrition can be caused by a lack of energy or protein which results in a decrease in muscle mass due to ... -
Efek Imunomodulator Ekstrak Etanol Daun Pirdot (Saurauia vulcani Korth ) terhadap Profil Sel T CD4+ Hepar dan Kadar IL 2 Serum pada Tikus Galur Wistar yang Diinduksi Salmonella typhimurium
(Universitas Sumatera Utara, 2023)Salmonella typhimurium is an intracellular bacteria that can affect the immune system so that an immunomodulator is needed to modulate the function and activity of the immune system. CD4+ and IL2 T cells are one of the ... -
Efek Antiinflamasi Ekstrak Ikan Gabus (Channa Striata) pada Tikus Model Pneumonia yang di Induksi dengan LPS E. Coli Secara Intratrakeal
(Universitas Sumatera Utara, 2023)Nosocomial pneumonia is an infection of the lungs that occurs after being treated in a hospital. Pneumonia is generally caused by Escherichia coli which causes acute inflammation and respiratory distress. The interaction ... -
Pengaruh Suhu dan Konsentrasi EDTA terhadap Inaktivasi DNase I untuk Preservasi DNA Asal Saliva
(Universitas Sumatera Utara, 2023)Background: Deoxyribonuclease I (DNase I) catalyzes the endonucleolytic cleavage of double stranded DNA into phosphodinucleotides and phosphooligonucleotides. DNase inactivation is influenced by EDTA, pH, and temperature. ... -
Polimorfisme Gen Leptin -2548G>A(RS7799039) dan Gen Ghrelin LEU72MET(RS696217) pada Penderita DM Tipe 2 di Kota Medan
(Universitas Sumatera Utara, 2023)Diabetes Mellitus type 2 is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion and insulin action or both which can be caused by environmental influences in the form of lifestyle, ...
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