Master Theses (Clinical Medicine)
Master Theses (Clinical Medicine)
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Pengaruh Kemoterapi terhadap Kesehatan Mata pada Leukemia Limfoblastik Akut Fase Induksi di Rumah Sakit Adam Malik Medan
(Universitas Sumatera Utara, 2025)Background: Leukemia is the most common malignancy in children and may cause multisystem involvement, including ocular structures. Ocular manifestations of leukemia include retinal hemorrhage, papilledema, and leukemic ... -
Hubungan Penyakit Jantung Bawaan Berdasarkan Pirau terhadap Kejadian Pneumonia
(Universitas Sumatera Utara, 2025)Background: Congenital Heart Disease (CHD) in children is frequently associated with lower respiratory tract infections, particularly pneumonia. Pneumonia risk in CHD is influenced by shunt type, defect size, nutritional ... -
Hubungan Rasio Neutrofil Limfosit dengan Ketuban Pecah Dini di RS Adam Malik dan RS Jejaring
(Universitas Sumatera Utara, 2025)Background: Premature rupture of membranes (PROM) is the spontaneous rupture of the amniotic sac before the onset of labor. Premature rupture of membranes (PROM) is often caused by infection. Infection may lead to ... -
Hubungan Antara Atherogenic Index Of Plasma (AIP) Terhadap Severitas Lesi Koroner Pada Pasien Infark Miokard Akut Non St-Elevasi Di Rsup Haji Adam Malik Medan
(Universitas Sumatera Utara, 2025)Introduction: Dyslipidemia is a major risk factor for coronary artery disease (CAD). This study aims to investigate the relationship between atherogenic index of plasma (AIP) and coronary lesion severity in Non ST-Elevation ... -
Hubungan Kadar Asam Urat dengan Kejadian Ketuban Pecah Dini di RS Adam Malik dan Rumah Sakit Jejaring
(Universitas Sumatera Utara, 2026)Background: Premature rupture of membranes (PROM) is an obstetric complication that contributes to maternal and perinatal morbidity. Uric acid has a dual role as an antioxidant; however, at higher levels it may promote ... -
Korelasi Bisprectral Index (BIS) dan Quantium Consciousness Index (QCON) dengan Richmond Agitation Sedation Scale (RASS) dalam Menilai Kedalaman Sedasi pada Pasien Pascaoperasi dengan Teknik Anestesi Umum yang Tersedasi di Ruang Rawat Intensif
(Universitas Sumatera Utara, 2025)Introduction: Adequate postoperative sedation plays a crucial role in preventing agitation and improving the effectiveness of intensive care. The Richmond Agitation– Sedation Scale (RASS) is routinely used to assess ... -
Hubungan antara Kadar Malondialdehid dengan Tingkat Keparahan Gejala Motorik dan Fungsi Kognitif Pasien Penyakit Parkinson
(Universitas Sumatera Utara, 2025)Background: Oxidative stress is suspected to play a role in the pathogenesis of Parkinson’s disease (PD) through the production of reactive oxygen species (ROS), which can lead to the loss of dopaminergic neurons. Post-mortem ... -
Perbandingan Pemberian Lidokain Intravena Kontinu dengan Pemberian Fentanyl Berdasarkan Hasil Kortisol Serum Selama Operasi Laparotomi di RS Adam Malik Medan
(Universitas Sumatera Utara, 2025)Background: Surgical procedures, such as laparotomy, induce significant stress responses characterized by activation of the hypothalamic-pituitary-adrenal (HPA) axis and increased serum cortisol levels. Attenuating this ... -
Efikasi Peperomia Pellucida Nanoemulsi dalamMencegah Infeksi Luka Operasi Setelah Laparatomy: A Randomized Control Trial
(Universitas Sumatera Utara, 2025)Background: Surgical site infection (SSI) post-laparotomy significantly increases morbidity, mortality, and healthcare costs. This study evaluates the efficacy of Peperomia pellucida nanoemulsion cream in preventing SSI ... -
Klinikopatologi Kanker Payudara Tipe HER2 di RSUP H. Adam Malik
(Universitas Sumatera Utara, 2025)Background: HER2-positive breast cancer represents 15-20% of cases worldwide, characterized by HER2 overexpression leading to aggressive proliferation via PI3K/AKT and MAPK pathways, poor prognosis, and high metastasis ... -
Perbandingan Nilai Diagnostik Calretinin dengan S100 sebagai Marker Imunohistokimia dalam Menegakkan Diagnosa Hirschsprung Disease di RS Adam Malik Medan
(Universitas Sumatera Utara, 2025)Background: Hirschsprung Disease (HSCR) is a congenital disorder due to neural crest cell migration failure, causing ganglion cell absence in the distal bowel segment and functional obstruction with incidence 1:5000 live ... -
Korelasi Ekspresi X-Linked Inhibitor of Apoptosis Protein (XIAP) terhadap Resistensi Kemoterapi pada Model Kanker Payudara Tripel Negatif MDA-MB 231 secara in vitro
(Universitas Sumatera Utara, 2025)Introduction: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options and a high rate of chemotherapy resistance. Inhibition of apoptosis is a key mechanism contributing ... -
Hubungan antara Kadar Zinc Serum dengan Ukuran Lesi Kondiloma Akuminata pada Pasien Human Immunodeficiency Virus
(Universitas Sumatera Utara, 2025)Background: Condyloma acuminata (CA) is a genital wart caused by HPV types 6 and 11, and is considered the most common sexually transmitted disease. In HIV patients, HPV infections are often more severe, with larger CA ... -
Perbedaan Nilai Prothrombin Time dan activated Partial Thromboplastin Time pada Sampel Ikterik dengan Metode Optikal dan Metode Elektromekanik
(Universitas Sumatera Utara, 2025)Background: Prothrombin time (PT) and activated partial thromboplastin time (aPTT) tests are important screening tests for assessing coagulation pathway function and monitoring anticoagulant therapy. These tests use ... -
Hubungan Triglyceride Glucose Index (Tyg Index) dengan Neuropati Diabetik Perifer (NDP) Berdasarkan Skor Michigan Neuropathy Screening Instrument (Mnsi) pada Diabetes Melitus Tipe 2
(Universitas Sumatera Utara, 2025)Background: Type 2 diabetes mellitus (T2DM) is one of the most common metabolic disorders worldwide and a major cause of morbidity and mortality due to chronic complications, including peripheral diabetic neuropathy ... -
Hubungan CRP, LED, dan Rasio Neutrofil Limfosit terhadap Keparahan Ulkus Diabetikum di RSUP Haji Adam Malik Medan
(Universitas Sumatera Utara, 2025)Introduction. Diabetes mellitus (DM) is a chronic disease with increasing prevalence and frequent complications in the form of diabetic ulcers, which contribute to high amputation and mortality rates. Diabetic ulcers ... -
Hubungan Systemic Inflammation Response Index (Siri) dan Systemic Immune Inflammation Index (Sii) dengan Stadium Kanker Kolorektal pada Pasien Kanker Kolorektal
(Universitas Sumatera Utara, 2024)Background: Colorectal cancer (CRC) represents a significant global health concern, associated with considerable morbidity and mortality. The Systemic Inflammation Response Index (SIRI) and the Systemic Immune Inflammation ... -
Hubungan Rasio Albumin Kreatinin Urin (uACR) terhadap Kejadian Acute Kidney Injury pada Pasien Sepsis di RS Adam Malik
(Universitas Sumatera Utara, 2025)Background: Sepsis is the most common cause of Acute Kidney Injury (AKI). Diagnosis of AKI based on serum creatinine (sCr) has limitations, sCr increases only after >50% kidney function is lost. uACR examination is a ... -
Hubungan Blood Urea Nitrogen dengan Left Ventricular Ejection Fraction pada Pasien Sindrom Koroner Akut di RS Adam Malik Medan
(Universitas Sumatera Utara, 2025)Background: Acute Coronary Syndrome (ACS) is a leading cause of cardiovascular morbidity and mortality. Reduced left ventricular ejection fraction (LVEF) and elevated blood urea nitrogen (BUN) have been associated ... -
Hubungan Kadar Cathelicidin terhadap Kualitas Hidup Pasien Prolapse Menggunakan P-Qol (Prolapse Quality of Life Questionnaire) dan Derajat III - IV Prolaps Organ Panggul di RS Prof. Dr. Chairuddin P. Lubis Universitas Sumatera Utara Medan dan RSUD Pirngadi Medan
(Universitas Sumatera Utara, 2025)Background: Pelvic organ prolapse (POP) is a common pelvic floor disorder in older women and significantly affects quality of life. The severity of POP is thought to be associated with alterations in the pelvic tissue ...
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