Analisis Faktor yang Memengaruhi Luaran Pengobatan (Therapeutic Outcomes) Penderita Kanker Serviks Stadium Lanjut Di RSUP. H. Adam Malik Tahun 2024 – 2025

Abstract

Background. Cervical cancer is one of the malignancies with high morbidity and mortality rates in Indonesia, particularly when patients present at an advanced stage. Treatment outcomes in advanced-stage cervical cancer are influenced by several factors, including disease stage, histopathological type, and duration of therapy. Therapeutic response in cervical cancer is clinically assessed using RECIST criteria, which categorize outcomes into Complete Response, Partial Response, and Progressive Disease. Objective. To determine the factors influencing treatment outcomes in patients with advanced-stage cervical cancer at RSUP H. Adam Malik in 2024–2025. Methods. This study employed an observational analytic method with a cross-sectional design. Data were obtained from medical records at RSUP H. Adam Malik during the period of January 2024 to May 2025, with a total sample of 84 patients selected using the total sampling technique. Data were analyzed using univariate, bivariate, and multivariate statistical tests. Results. Of the 84 patients, the majority were aged >50 years (54.8%), multiparous (59.5%), had ≤1 sexual partner (91.7%), were diagnosed at stage II B (32.1%), had non- keratinizing squamous cell carcinoma histopathology (44.0%), underwent treatment for >3 months (64.3%), and achieved Complete Response (63.1%). Based on bivariate analysis, cervical cancer stage, histopathology type, and duration of treatment were not associated with treatment outcomes. Conclusion. Cancer Stage, histopathology type, and duration of treatment were not significantly associated with treatment outcomes in advanced cervical cancer.