Hubungan Indeks Aterogenik Plasma dan Skor Thrive Terhadap Luaran Klinis Pasien Stroke Iskemik Akut Di Rumah Sakit Adam Malik Medan

Abstract

Background: The atherogenic index of plasma is a biochemical parameter used to assess the risk of atherosclerosis disease. The Totaled Health Risks in Vascular Events (THRIVE) score is a predictive tool for estimating clinical outcomes and mortality in patients with acute ischemic stroke. Patients with higher AIP have an increased risk of atherosclerosis, which may also be reflected in elevated THRIVE scores. Therefore, combining these two assessment tools may help predict clinical outcomes and guide more effective management strategies for acute ischemic stroke patients. Objective: To analyze the association between IAP and THRIVE score with clinical outcomes in acute ischemic stroke patients at Adam Malik Hospital, Medan. Methods: This cross-sectional study included 51 acute ischemic stroke patients hospitalized at Adam Malik Hospital, Medan, who met the inclusion and exclusion criteria. IAP was calculated using the logarithm of the ratio of serum triglycerides to HDL-C. The THRIVE score was determined based on age, hypertension, diabetes, and NIHSS on the first day of admission. Clinical outcomes were assessed using the modified Rankin Scale (mRS) on the seventh day of hospitalization. Data were analyzed using SPSS with using SPSS with the Gamma correlation test. Results: here was no significant relationship between IAP and clinical outcomes of acute ischemic stroke patients assessed by mRS score (r = -0.143; p = 0.844). There was a significant relationship between THRIVE score and clinical outcomes of acute ischemic stroke patients based on mRS (r = 0.933; p < 0.001). Discussion: The THRIVE score is associated with clinical outcomes in acute ischemic stroke patients.