Perbedaan Efek Inhibisi Propolis Geniotrigona Thoracica Dalam Bentuk Ekstrak Dan Chip Hidrogel Terhadap Porphyromonas gingivalis: Studi Eksperimental In Vitro

Abstract

The global prevalence of periodontal disease is estimated to range from 20% to 50%, making it one of the most common oral health problems in the world, so it is necessary to conduct research to develop a periodontal chip containing propolis extract for comparative analysis of its inhibitory effect with Geniotrigona thoracica propolis extract against Porphyromonas gingivalis bacteria. Therefore, this study aims to show that propolis has strong potential as an antibacterial agent against Porphyromonas gingivalis, both in the form of extracts and periodontal chips in supporting the development of alternative therapies based on natural ingredients as a complement to periodontitis treatment based on the diameter of the inhibition zone produced. This study is an in vitro laboratory experimental study with a posttest control group design, comparing the inhibitory power of Geniotrigona thoracica propolis extract with a control group, comparing Geniotrigona thoracica propolis periodontal chip with a control group, and comparing Geniotrigona thoracica propolis extract with Geniotrigona thoracica propolis periodontal chip. The results of the study were a comparison of the inhibition zone of Geniotrigona thoracica propolis extract with the control group (P<0.05), a comparison of Geniotrigona thoracica propolis periodontal chip with the control group (P<0.05), and a comparison of Geniotrigona thoracica propolis extract with Geniotrigona thoracica propolis periodontal chip (P<0.05). The conclusion of this study is that propolis has strong potential as an antibacterial agent against Porphyromonas gingivalis, both in the form of extracts and periodontal chip. This supports the development of alternative therapies based on natural ingredients as a complement to periodontitis treatment.