Faculty of Pharmacy: Recent submissions
Now showing items 41-60 of 2504
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Efek Antikanker Ekstrak Etanol, Fraksi n-Heksan dan Etil Asetat Daun Pirdot (Saurauia vulcani Korth.) pada Sel Kanker Payudara 4T1
(Universitas Sumatera Utara, 2025)Background: Breast cancer is a malignant tumor that appears in breast tissue, both in the epithelium of the ducts and lobules. Various therapeutic methods have been developed, one of which is chemotherapy. However, ... -
Penerapan Green Extraction dalam Meningkatkan Kadar Berberine Ekstrak Batang Brotowali (Tinospora crispa (L.) Hook.f. & Thomson) dan Aktivitas Sitotoksiknya terhadap Sel Kanker Serviks
(Universitas Sumatera Utara, 2025)Background: Cervical cancer continues to be a significant health issue with high prevalence and mortality rates. Brotowali (Tinospora crispa (L.) Hook.f. & Thomson) is a medicinal plant known to exhibit cytotoxic activity ... -
Studi Etnomedisin Tumbuhan Berkhasiat Sebagai Antidiabetes dan Antikanker di Kecamatan Kabanjahe Kabupaten Karo
(Universitas Sumatera Utara, 2025)Background: Type 2 diabetes mellitus and cancer are major global health issues with high incidence rates, including in Indonesia. In Kabanjahe District, Karo Regency, still has abundant natural resources and has traditionally ... -
Uji In Silico Peptida Bioaktif dari Protein Globulin 13S dan Albumin Biji Fagopyrum esculentum Terhadap Dipeptidyl Peptidase-IV
(Universitas Sumatera Utara, 2025)Background: Diabetes mellitus is a disease of blood glucose metabolism disorders. DM drugs that inhibit DPP-IV are at risk of causing side effects so that alternative natural treatments are needed. Buckwheat seeds are rich ... -
Pengaruh Makanan yang Mengandung Flavonoid Terhadap Biomarker Kesehatan Kardiovaskular: Studi Tinjauan Literatur Sistematis
(Universitas Sumatera Utara, 2025)Background: Cardiovascular disease is one of the most prevalent non-communicable diseases. Current therapeutic approaches have several limitations, highlighting the need for safer and more efficient alternative therapies. ... -
Aktivitas Antidepresan Ekstrak Air Buah Haritaki (Terminalia chebula Retz.) pada Mencit yang Diinduksi Chronic Unpredictable Stress (CUS)
(Universitas Sumatera Utara, 2025)Background: depression is a chronic mental disorder that has a significant impact on global well-being. Imbalances in neurotransmitters such as serotonin and dopamine contribute to the pathophysiology of depression. The ... -
Pengaruh Ekstrak Etanol Bawang Hitam Tunggal (Allium sativum L. var. solo garlic) Terhadap Respon Koordinasi Motorik Tikus Yang Diinduksi Paraquat
(Universitas Sumatera Utara, 2025)Background: Solo black garlic is a fermented product of single clove garlic, known to enhance bioactive compounds. Previous research suggests this enhancement has neuroprotective potential, including in motor coordination ... -
Uji Aktivitas Kardioprotektif Ekstrak Etanol Daun Salam (Syzygium polyanthum [Wight] Walp.) Pada Tikus Yang Diinduksi Dengan Doksorubisin
(Universitas Sumatera Utara, 2025)Background: Cardiovascular disease is one of the leading causes of death globally, with doxorubicin being an effective antineoplastic agent but having significant cardiotoxicity side effects. The use of cardioprotective ... -
Pengaruh Ekstrak Etanol Buah Biwa (Eriobotrya Japonica (Thunb.) Lindl.) terhadap Regulasi Jalur Mapk dalam Induksi Apoptosis pada Sel CT-26
(Universitas Sumatera Utara, 2025)Background: Colorectal cancer is the top three leading causes of cancer-related deaths globally. The MAPK pathway plays a critical role in regulating apoptosis, proliferation, and migration, making it a potential target ... -
Formulasi Nanoemulsi Hair Tonic Ekstrak Etanol Batang Teras Bakau Api-Api (Avicennia marina (Forssk.) Vierh) dan Uji Aktivitas Terhadap Pertumbuhan Rambut Tikus
(Universitas Sumatera Utara, 2025)Background : Api-api mangrove (Avicennia marina) heart wood contain various bioactive compounds consisting of polyphenols, flavonoids, tannins, terpenoids, alkaloids, saponins, and anthraquinones that have activity in hair ... -
Uji Aktivitas Hemostasis dan Penyembuhan Luka Gel Ekstrak Pegagan (Centella asiatica (L.) Urban) pada Tikus Putih (Rattus norvegicus)
(Universitas Sumatera Utara, 2025)Background: Wounds and hemostasis disorders are conditions that often occur and require effective treatment. Gotu kola (Centella asiatica (L.) Urban) is known to have triterpenoid compounds that can accelerate wound ... -
Uji Efek Gastroprotektif Kapsul Campuran Ekstrak Etanol Herba Pegagan, Herba Sambiloto, dan Rimpang Temu Giring pada Kelinci yang Diinduksi Asetosal
(Universitas Sumatera Utara, 2025)Background: Gastric ulcers are a gastrointestinal disorder that can be induced by side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin. Mucosal damage caused by aspirin is triggered by reduced ... -
Tingkat Pengetahuan dan Perilaku Orang Tua terhadap Penggunaan Antibiotik pada Anak di Puskesmas Marubun Jaya Kecamatan Tanah Jawa Kabupaten Simalungun
(Universitas Sumatra Utara, 2025)Background: Inappropriate antibiotic use in children is a global health problem, with prevalence in Indonesia reaching 40% - 60%. Parents' knowledge about antibiotic use is very important to reduce the risk of antimicrobial ... -
Determinasi Kadar Total Fenol, Flavonoid dan Antioksidan dari Ekstrak Etanol dan Ekstrak Kaya Polifenol Herba Pegagan (Centella asiatica (L.) Urb.)
(Universitas Sumatera Utara, 2025)the acquisition of a level of active substance compounds, one of which is the variation of the extraction method used. Objective: This study aims to compare the levels of total phenols, flavonoids and antioxidant activity ... -
Tingkat Pengetahuan dan Perilaku Orang Tua terhadap Penggunaan Antibiotik pada Anak di Puskesmas Kenangan Kecamatan Percut Sei Tuan Deli Serdang
(Universitas Sumatera Utara, 2025)Background: Inappropriate use of antibiotics in children increases the risk of resistance, which currently causes around 700.00 deaths per year and is projected to rise to 10 million by 2050. Therefore, parents’ knowledge ... -
Uji Efek Penyembuhan Luka Sediaan Hidrogel Campuran Ekstrak Etanol Daun Jeruju (Acanthus ilicifolius Linn.) dan Kitosan pada Luka Bakar
(Universitas Sumatera Utara, 2025)Background: Jeruju (Acanthus ilicifolius Linn.) contains efficacious compounds such as alkaloids, flavonoids, steroids, and tannins that have biological activities included antibacterial, anti-inflammatory, and antioxidant ... -
Tingkat Pengetahuan dan Perilaku Orang Tua terhadap Penggunaan Antibiotik pada Anak di UPT Puskesmas Kota Matsum Kota Medan
(Universitas Sumatera Utara, 2025)Background: Infectious diseases remain among the most significant global health challenges, accompanied by a notable rise in antibiotic consumption. Misuse or overuse of antibiotics can contribute to the development of ... -
Uji Toksisitas Akut Ekstrak Etanol Daun Attarasa (Litsea Cubeba (Lour.) Pers.) Secara Oral pada Mencit Putih
(Universitas Sumatera Utara, 2025)Background: Attarasa (Litsea cubeba (Lour.) Pers.) is a plant widely found in Indonesia, particularly North Tapanuli, and is used as a traditional medicine. This study evaluated the acute toxicity of ethanol extract of ... -
Uji In Vitro Ekstrak Etanol Daun Attarasa (Litsea cubeba (Lour.) Pers.) Terhadap Sel Kanker CT-26
(Universitas Sumatera Utara, 2025)Background: Colorectal cancer, a prevalent global malignancy, faces treatment challenges due to drug resistance and toxicity. Litsea cubeba, a plant with bioactive compounds, exhibits antibacterial, anti-inflammatory, and ... -
Studi Potensi Senyawa Golongan Flavonoid Daun Gagatan Harimau (Ampelocissus thyrsiflora (Blume) Planch) terhadap CHK2 dan WEE1 secara In Silico
(Universitas Sumatera Utara, 2025)Background: Lung cancer is one of the leading causes of death worldwide, with a low survival rate due to late diagnosis. CHK2 and WEE1 are two proteins involved in cell cycle regulation, and their inhibition has the potential ...