Faculty of Pharmacy: Recent submissions
Now showing items 61-80 of 2504
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Formulasi dan Uji Aktivitas Antibakteri Sediaan Nanoemulgel Minyak Atsiri Rosemari (Rosmarinus officinalis L.) Terhadap Propionibacterium acnes dan Staphylococcus epidermidis
(Universitas Sumatera Utara, 2025)Background: Acne is caused by several bacteria including Propionibacterium acnes and Staphylococcus epidermis. Essential oil from rosemari is known to contain various antibacterial components. However, the hydrophobic ... -
Studi Network Pharmacology dan Molecular Docking Senyawa Golongan Flavonoid Daun Gagatan Harimau (Ampelocissus thyrsiflora (Blume) Planch) pada Kanker Payudara
(Universitas Sumatera Utara, 2025)Background: Triple negative breast cancer is the most aggressive type of breast cancer. Most experience recurrence within 1 to 2 years and only about 30% of patients have a survival rate of more than 5 years. Tiger ... -
Optimasi Ekstraksi Total Fenol dari Batang Bakau Api-Api (Avicennia marina) dengan Metode Microwave Assisted Extraction Menggunakan Box Behnken Design (BBD)
(Universitas Sumatera Utara, 2025)Background: The stem of the grey mangrove (Avicennia marina) contains abundant secondary metabolites, including phenolic compounds with bioactive potential. One of the techniques for extracting these compounds is ... -
Uji Aktivitas Penghambatan Enzim Tirosinase secara In Vitro dari Ekstrak Etanol Daun Sijukkot (Lactuca indica L.)
(Universitas Sumatera Utara, 2025)Background: The rising of hyperpigmentation prevalence has become a worldwide problem and a natural based brightening agent is needed. Sijukkot (Lactuca indica L.) is native plants to North Sumatera which are utilized by ... -
Formulasi Sediaan Hidrogel Ekstrak Etanol Daun Tapak Dara (Catharanthus roseus L.) dan Uji Efektivitas Penyembuhan Luka Sayat pada Tikus
(Universitas Sumatera Utara, 2025)Background: Cathranthus roseus leaves contain alkaloid, tannin and flavonoid compounds that can play a role in accelerating wound healing. Hydrogel preparations can accelerate wound healing by rehydrating tissues without ... -
Pengaruh Metode Ekstraksi terhadap Kadar Fenol, Flavanoid dan Aktivitas Antioksidan Ekstrak Etanol Daun Karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.)
(Universitas Sumatera Utara, 2025)Background: There are several factors that affect a plant extract. This will affect the acquisition of a level of active substance compounds, one of which is the extraction method used. Objective: This study aims to ... -
Uji In Silico Hasil LC-HRMS dari Ekstrak Etanol Batang Bakau Api-Api (Avicennia marina) sebagai Inhibitor Angiotensin Converting Enzyme (ACE)
(Universitas Sumatera Utara, 2025)Background: : Hypertension is the leading cause of death worldwide each year and is categorized as a deadly disease, often referred to as a “silent killer.” The Angiotensin-Converting Enzyme (ACE) receptor plays a crucial ... -
Formulasi dan Evaluasi Blush On Stick dengan Pewarna Ekstrak Daun Bayam Merah (Amaranthus Tricolor L.)
(Universitas Sumatera Utara, 2025)Background: Red spinach leaves (Amaranthus tricolor L.) contain quite high anthocyanins with red pigments that have the potential as natural dyes and are relatively safer to use compared to synthetic dyes. Natural dyes ... -
Formulasi dan Uji Efektivitas Blush On Stick Ekstrak Daun Andong Merah (Cordyline fructicosa (L.) A.Chev.) Sebagai Perona Pipi
(Universitas Sumatera Utara, 2025)Background : Red andong leaves have red leaves that come from anthocyanins so they can be used as natural pigments or natural dyes that can be used as natural dyes in blush on stick preparations as blusher. Objective : ... -
Uji Efek Gastroprotektif Kapsul Campuran Ekstrak Etanol Herba Pegagan, Herba Sambiloto, dan Rimpang Temu Giring pada Kelinci yang Diinduksi Stres
(Universitas Sumatera Utara, 2025)Background: Peptic ulcers are caused by an imbalance between aggressive factors and gastric mucosal defenses. Synthetic treatments have side effects, so herbal alternatives are needed. Gotu kola, sambiloto, and temu giring ... -
Analisis Metabolit Sekunder Berdasarkan Gugus Fungsi Menggunakan Fourier Transform Infrared (FTIR) pada Umbi Bit (Beta vulgaris Lindl.)
(Universitas Sumatera Utara, 2025)Background: Beetroot (Beta vulgaris) is known to contain a diverse array of phytochemicals, particularly secondary metabolites such as flavonoids, alkaloids, saponins, and tannins. These compounds have attracted ... -
Pembuatan Isolat dan Penetapan Kadar Protein Kacang Edamame (Glycine max (L.) Merr) dengan Metode Kjeldahl dan Bradford
(Universitas Sumatera Utara, 2025)Background: Edamame beans have a fairly high protein content. To obtain pure protein, protein isolation is carried out. One alternative for obtaining protein isolate from edamame beans can be done using the acid-base method. ... -
Optimasi Mikroenkapsulasi Ekstrak Etanol Daun Karet Kebo (Ficus elastica Roxb. ex Hornem.) Menggunakan Kitosan dan Uji Aktivitasnya sebagai Antioksidan
(Universitas Sumatera Utara, 2025)Background: Karet kebo leaves have high potential as antioxidant and anti-inflammatory agent due to their rich flavonoid compounds, namely quercitrin, myricitrin, and kaempferol, which show stronger antioxidant activity ... -
Analisis Efektivitas Biaya (Cost Effectiveness Analysis) Pengobatan Hipertensi pada Pasien Penyakit Gagal Jantung Kongestif Di RSUP. H. Adam Malik Medan
(Universitas Sumatera Utara, 2024)Background: Cardiovascular diseases represented the most significant portion of catastrophic healthcare expenditure, comprising 49% of total Social Security Agency on Health claims. Of the total Rp 20 trillion in ... -
Analisis Komponen Kuersetin, Naringenin dan Kaempferol dalam Umbi Bit (Beta vulgaris Lindl.) secara UPLC MS/MS MRM
(Universitas Sumatera Utara, 2025)Background: Beet tubers (Beta vulgaris Lindl.) are known to contain bioactive compounds such as flavonoids that have potential as antioxidants, anti-inflammatory and antibacterial. Among these compounds, quercetin, ... -
Perbandingan Potensi Antioksidan Ekstrak Etanol Daun Gagatan Harimau (Ampelocissus thyrsiflora (Blume) Planch) dengan Metode DPPH, ABTS, dan FRAP
(Universitas Sumatera Utara, 2025)Background : Free radicals are reactive compounds that can cause oxidative stress and contribute to various degenerative diseases such as cancer, diabetes and cardiovascular disease. Antioxidants play an important role in ... -
Aktivitas Antidiabetes Senyawa Fenolik Umbi Bawang Batak (Allium chinense G. Don) melalui Pendekatan Network Pharmacology dan Molecular Docking
(Universitas Sumatera Utara, 2025)Background: Diabetes mellitus is a group of metabolic diseases with hyperglycemia due to impaired insulin secretion or function. Phenolic compounds as natural antioxidants can protect pancreatic beta cells from free ... -
Efek Pencegahan Iritasi Lambung dari Suspensi Ibuprofen Mengandung Natrium Alginat yang Dibandingkan dengan Larutan Natrium Alginat Sebelum Pemberian Suspensi Ibuprofen
(Universitas Sumatera Utara, 2025)Background: Ibuprofen is a medication that can cause stomach irritation through a local mechanism. Sodium Alginate has a protective effect on the stomach by forming a gel that helps protect the stomach lining. Objective: ... -
Kajian Ekstrak Kloroform : Metanol Xylocarpus granatum J. Koenig terhadap Regulasi Quorum Sensing Pseudomonas aeruginosa dan Methicillin-Resistant Staphylococcus aureus (MRSA)
(Universitas Sumatera Utara, 2025)Background: Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus (MRSA) are pathogenic bacteria that play a significant role in antibiotic resistance. The discovery of effective and safe natural remedies ... -
Nanosuspensi Parasetamol tanpa Surfaktan yang Dibuat Menggunakan Metode Dry-Milling: Formulasi, Uji In Vitro dan Uji Efek Antipiretik dan Analgetik
(Universitas Sumatera Utara, 2025)Background: Paracetamol is a drug with poor water solubility. Therefore, the preparation of paracetamol nanosuspension was carried out. However, in previous studies, the results of testing the pharmacological effects in ...