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    Korelasi Ghrelin Terhadap Densitas Tulang pada Wanita Menopause

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    fulltext (2.293Mb)
    Date
    2018
    Author
    Fakhrurrazi
    Advisor(s)
    Siregar, M. Fidel Ganis
    Prabudi, M. Oky
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    Abstract
    Penelitian ini merupakan penelitian deskriptif dengan pendekatan case Untuk mengetahui korelasi nilai ghrelin dengan densitas tulang pada wanita menopause. Penelitian ini dilakukan di SMF Obstetri dan Ginekologi RSUP H. Adam Mlaik- Departemen obstetri dan ginekologi FK USU dilakanakan Desember 2018 sampai Februari 2019. Sampel yang memenuhi kriteria inklusi dan eksklusi kemudian diambil darahnya dan diperiksa kadar Ghrelin serum kemudian dilakukan pemeriksaan Bone Mass Density (BMD). Lalu dilakukan analisa korelasi secara statistik untuk menilai hubungan kadar ghreline dan Bone Mass Density wanita Menopause. Dari hasil penelitian, Sebagian besar subjek penelitian tergolong dalam klasifikasi osteopenia yaitu sebanyak 23 orang (76.7%), pada penelitian ini juga terdapat 2 (6.7%) subjek yang mengalami osteoporosis dan sisanya dalam keadaan normal sebanyak 5 orang (16.7%). didapatkan adanya korelasi yang signifikan antara kadar ghrelin dengan densitas massa tulang (r = - 0,397; p = 0,030) dengan korelasi dengan r hitung untuk densitas massa tulang lebih besar dari r tabel dan bernilai negatif Penelitian ini menyimpulkan adanya korelasi yang signifikan antara kadar ghrelin dengan densitas massa tulang (r = - 0,397; p = 0,030) dengan korelasi dengan r hitung untuk densitas massa tulang lebih besar dari r tabel dan bernilai negatif.
     
    This research is a descriptive study with a case approach to determine the correlation of the value of ghrelin with bone density in menopausal women. This research was carried out at Obstetrics and Gynecology SMF at H. Adam Mlaik General Hospital. The USU Department of Obstetrics and Gynecology was conducted in December 2018 until February 2019. Samples that met the inclusion and exclusion criteria were then drawn for blood and examined for serum Ghrelin levels and Bone Mass Density (BMD) examination. ) Then a statistical correlation analysis was performed to assess the relationship between levels of ghreline and Bone Mass Density for Menopause women. From the results of the study, most of the research subjects belong to the classification of osteopenia as many as 23 people (76.7%), in this study there were also 2 (6.7%) subjects who had osteoporosis and the rest in normal conditions as many as 5 people (16.7%). there was a significant correlation between ghrelin levels and bone mass density (r = - 0.397; p = 0.030) with a correlation with r count for bone mass density greater than r table and positive This study concludes that there is a significant correlation between ghrelin levels and bone mass density (r = - 0.397; p = 0.030) with a negative correlation with r count for bone mass density greater than r table.

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    http://repositori.usu.ac.id/handle/123456789/12417
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    Repositori Institusi Universitas Sumatera Utara (RI-USU)
    Universitas Sumatera Utara | Perpustakaan | Resource Guide | Katalog Perpustakaan
    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV