| dc.description.abstract | Abstract
Background:
Allergic contact dermatitis (ACD) is skin inflammation which is a T cell mediated
caused by recurrent contact to the hapten in sensitized individual. Cluster of
differentiation 4+ (CD4+) and cluster of differentiation 8+ (CD8+) T cells have
roles in allergic contact dermatitis pathogenesis.
Objective:
The aimed of the study is to investigate the levels of Cluster of differentiation 4+
(CD4+) and cluster of differentiation 8+ (CD8+) T cells in allergic contact
dermatitis patients in the Division of the Immunodermatology, Department of
Dermatology and Venereology, Haji Adam Malik general hospital Medan
Methods:
The design of the study is a cross sectional descriptive. Sample was taken using
consecutive sampling. Sera were collected from forty five patients with allergic
contact dermatitis for FASCanto analysis to evaluate levels of CD4+ and CD8+ T
cells.
Results:
We had forty five samples with woman predominance; The highest frequency was
≤ 31 years old. The most ocupational in ACD patients was non goverment
empleyee. CD4+ and CD8+ T cells serum concentration mean and standard
deviation are 851,27 ± 242,487 sel/μL and 732,69 ± 252,307sel/μL respectively.
Conclusion:
These findings suggest mean level of CD4+ T cells is 851,27 sel/μL and mean
level of CD8+ T cells is 732,69 sel/μL. | en_US |
