Hubungan Gangguan Libido Wanita Menurut Kuisioner DSDS (Decreased Sexual Desire Screener) dengan Kadar Testosteron Saliva pada Surgical Menopause

Abstract

Tujuan: Untuk mengetahui hubungan kadar testosteron saliva dengan libido. Metode: Penelitian ini merupakan penelitian analitik observatif dengan pendekatan studi case control dengan menggunakan kuesioner Decreased Sexual Desire Screener (DSDS) dengan jumlah sampel penelitian sebanyak 54 orang wanita yang terbagi menjadi kelompok kasus yaitu 27 orang wanita surgical menopause di RSUP H. Adam Malik dan Pirngadi dengan kelompok kontrol yang terdiri dari 27 orang wanita normal yang memenuhi kriteria penelitian. Pasien yang sesuai kriteria inklusi diperiksa kadar FSH dalam darah (kelompok kasus) dan testosterone saliva. Selanjutnya dilakukan wawancara dengan kuesioner DSDS. Data dianalisis dan uji dianggap bermakna bila nilai P<0.05. Hasil: Berdasarkan hasil penelitian didapatkan rerata kadar FSH pada kelompok kasus adalah 59,29 mIU/ml dengan SD = 15,15 mIU/ml. Rerata kadar testosteron pada kelompok kasus adalah 22,41 pg/ml sedangkan pada kelompok kontrol 44,22 pg/ml dengan nilai p<0,001. Pada kelompok subyek dengan surgical menopause terdapat 20 orang (74,1%) mengalami gangguan libido, sementara itu pada kelompok kontrol hanya terdapat 5 orang (18,5%) yang mengalami gangguan libido dengan nilai p<0,001 (OR = 12,571, 95% IK = 3,434 – 46,018). Subyek wanita dengan surgical menopause berisiko sebesar 12,571 kali mengalami gangguan libido dibanding kelompok kontrol. Kesimpulan: Terdapat hubungan yang signifikan antara kadar testosteron saliva dengan gangguan libido.

Objective: To determine the relationship of salivary testosterone levels with libido. Method: This study was an observational analytic study with a case control study approach using the Decreased Sexual Desire Screener (DSDS) questionnaire with a total sample of 54 women divided into case groups: 27 surgical menopausal in the H. Adam Malik General Hospital and Pirngadi Hospital with control group consisting of 27 normal women who met the study criteria. Patients who were according to the inclusion criteria were examined blood FSH levels (for surgical menopause) and testosterone saliva obtained from the patient's saliva sample. Then interviews were carried out with DSDS questionnaire. Data were analyzed and the test was considered significant if the P value <0.05. Result: Based on the results of the study it was found that the mean FSH level in the case group was 59.29 mIU / ml with SD = 15.15 mIU / ml. The average testosterone level in the case group was 22.41 pg / ml while in the control group it was 44.22 pg / ml with a p value <0.001. In the group of subjects with surgical menopause there were 20 people (74.1%) having a libido disorder, while in the control group there were only 5 people (18.5%) who had a libido disorder with a p value <0.001 (OR= 12.571, 95% CI = 3,434 - 46,018). Subjects of women with surgical menopause had a risk of 12,571 times experiencing libido disorders compared to the control group. Conclusion: There was a significant correlation between salivary testosterone levels with libido disorders.