Hubungan Peningkatan Laktat Darah Terhadap Left Ventricle Ejection Fraction (Lvef) Pasien St Elevasi Miokard Infark (Stemi) di Rs Haji Adam Malik Medan Tahun 2019

Abstract

Introduction : Cardiovascular disease is the leading cause of death in the world. Knowing early heart attack is very important. Lactic acid will increase and LVEF will decrease during a heart attack. Aim : To investigate the relationship of increasing lactic acid levels with a decrease Left Ventricle Ejection Fraction patients in STEMI. Methods : A prospective study of 45 STEMI patients who came to the Haji Adam Malik Central General Hospital Medan from March to April 2019. Assessment of blood lactic acid levels with venous blood examination and LVEF through Echocardiography. Univariate, bivariate using Chi Square analysis with SPSS version 21. Results : Patients with lactic acid ≥ 2.5 mmol / l as much as 40%, while LVEF is good at 42%. Chi square examination results showed the relationship between lactic acid and LVEF with p = 0.03 and OR = 9.1 Conclusion : There was a significant relationship between the increase in lactic acid levels and a decrease in LVEF in STEMI patients.

Latar Belakang : Penyakit jantung menjadi penyebab kematian terbanyak di dunia. Mengetahui serangan jantung dini sangatlah penting. Asaam laktat akan meningkat dan LVEF akan menurun pada saat serangan jantung. Tujuan : Mengetahui hubungan peningkatann kadar asam laktat dengan penurunan Left Ventricle Ejection Fraction pasien STEMI Metode : Penelitian prospektif terhadap 45 pasien STEMI yang datang ke Rumah Sakit Umum Pusat Haji Adam Malik Medan dari Maret - April 2019. Penilaian kadar asam laktat darah dengan pemeriksaan darah vena dan LVEF melalui Echocardiografi. Analisis univariat, bivariat (Chi Square) dengan SPSS versi 21. Hasil : Pasien dengan Asam laktat ≥ 2,5mmol/l sebanyak 40%, LVEF baik sedang LVEF baik terdapat pada 42%. Hasil pemeriksaan Chi square menunjukkan hubungan antara asam laktat dan LVEF dengan p=0,03 dan OR=9,1 Kesimpulan : Terdapat hubungan yang bermakna antara peningkatan kadar asam laktat dengan penurunan LVEF pasien STEMI.