Perbedaan Rerata Intensitas Nyeri Analgesik Tramadol Dengan Asam Mefenamat Terhadap Nilai Universal Pain Assesment Tool (UPAT) Pada Pasien Pasca Operasi Seksio Sesarea

Abstract

Latar Belakang: Nyeri pasca operasi menyebabkan ketidaknyamanan pasien, penurunan tingkat kepuasan, pemulihan berkepanjangan, dan biaya perawatan kesehatan yang lebih tinggi. Saat ini tidak ada standar emas untuk manajemen nyeri seksio sesarea Tujuan: Membandingkan rerata intensitas nyeri agen tunggal oral tramadol 50 mg dengan agen tunggal asam mefenamat oral 500 mg dalam 12 jam pasca operasi seksio sesarea Metode: Desain penelitian adalah uji klinis acak terkontrol (Randomized Clinical Trial) dengan rancangan one group post test design. Subjek dibagi atas 2 kelompok yaitu kelompok asam mefenamat dan kelompok tramadol dengan masing-masing jumlah sampel adalah 25 orang. Pemberian analgetik diberikan 12 jam pasca operasi seksio sesarea dan dilakukan penilaian UPAT serta efek samping obat 1 jam dan 2 jam berikutnya Hasil: Intensitas nyeri pada kelompok tramadol adalah intensitas nyeri ringan (64%) setelah1 jam pemberian dan tidak ada nyeri (48%) setelah 2 jam pemberian, sedangkan pada kelompok asam mefenamat menunjukkan intensitas nyeri sedang (60%) pada 1 jam setelah pemberian dan masih sedang (60%) pada 2 jam pemberian. Terdapat perbedaan intensitas nyeri secara signifikan setelah 1 jam (p=0,002) dan 2 jam (p=0,002) pemberian obat antara kelompok yang diberikan tramadol dibandingkan dengan kelompok pemberian asam mefenamat. Kesimpulan: Pemberian tramadol oral memberikan efek analgetik yang lebih baik dibandingkan asam mefenamat untuk mengatasi nyeri pasca operasi seksio sesarea

Background: Postoperative pain causes patient discomfort, decreased satisfaction levels, prolonged recovery, and higher health care costs. There is currently no gold standard for the management of cesarean section pain and there have been no studies on the effectiveness of using oral opioids such as oral tramadol in the management of post-cesarean section pain. Objective: To compare the mean pain intensity of oral single agent tramadol 50 mg with oral single agent mefenamic acid 500mg within 12 hours after cesarean section. Methods: The study design was randomized clinical trial with a one group posttest design. Subjects were divided into 2 groups, namely the mefenamic acid group and the tramadol group with 25 people for each. Analgetics have given after 12 hours post cesarean section, evaluate UPAT and side effects of drugs 1 hours then 2 hours after that. Results and Discussion: The pain intensity in the tramadol group was mild pain intensity (64%) after 1 hour of administration and no pain (48%) after 2 hours of administration, whereas in the mefenamic acid group showed moderate pain intensity (60%) at 1 hour after administration. giving and still being (60%) at 2 hours of administration. There was a significant difference in pain intensity after 1 hour (p = 0.002) and 2 hours (p = 0.002) of drug administration between the groups given tramadol compared with the mefenamic acid group. Conclusion: The analgetic effect of oral tramadol is better than mefenamic acid for pain management after cesarean section