dc.description.abstract | Ovarian cancer is a gynecologic malignancy derived from ovarian tissue. There are several factors that can affect the occurrence of ovarian cancer such as age, Body Mass Index (IMT), pregnancy and parity, history of surgery, estrogen and hormone therapy, family history with cancer, diet, and consumption of alcohol and cigarettes
The present study is qualitative descriptive research aimed at obtaining the descriptive of characteristic of the patients with epithelial ovarian cancer based on age, parity, CA-125, RMI, histopathology, disease stage and surgery at RSUP Haji Adam Malik 2010-2014. The samples of the study included all epithelial ovarian cancer patients recorded in the Department of Obstetrics and Gynecology Haji Adam Malik Hospital started during the period January 2013 until December 2016 which amounted to 42 persons.
The results of the study showed that majority of the samples aged 41-60 years old as of 28 persons (66.7%) and majority of them was multipara ie as many as 16 persons (38.1%). Majority of samples had a CA-125 tumour marker level greater than 35, 37 (88.1%) with RMI more than 200, 32 (50.0%), suffering from serous adenocarcinoma 24 persons (57.1%), had an advanced stage ie as many as 22 persons (52.4%) and majority of the sample undergo surgery Laparotomy Surgical Staging (LSS) that is as of 36 persons (85.7%). It is suggested to H. Adam Malik General Hospital Medan to further improve the completeness of medical record data, especially about epithelial ovarian carcinoma so many aspects required such as RMI data, examination of CA 125, histopathology, stage and operation action have more accurate and complete data.
Majority of the the samples had age ranging 41-60 years old as of 53 persons (63.1%) and in general the sample was multipara ie as of 27 persons (31.2%). The majority of samples had levels of CA-125 tumor marker greater than 35, 57 (67.9%), had more than 200 RMI’s (42 persons (50.0%), suffered serous adenocarcinoma (38.2%), advanced stage ie as of 33 persons (39.3%) and majority of the samples undergo surgery Laparotomy Surgical Staging (LSS) as of 51 persons (60.7%). To RSUP H. Adam Malik Medan is suggested to further improve the completeness of medical record data, especially about epithelial ovarian carcinoma so aspect aspect required such as RMI data, examination of CA-125, histopathology, stage and operation action have more accurate and complete data. | en_US |
dc.description.abstract | Kanker ovarium merupakan keganasan ginekologik yang berasal dari jaringan ovarium. Ada beberapa faktor yang dapat memengaruhi terjadinya kanker ovarium. Faktor risiko itu berupa usia, Indeks Massa Tubuh (IMT), kehamilan dan paritas, riwayat operasi, terapi estrogen dan hormon, riwayat keluarga dengan kanker, pola makan, serta konsumsi alkohol dan rokok.
Penelitian ini merupakan penelitian deskriptif kualitatif untuk memperoleh gambaran karakteristik penderita kanker ovarium epitel berdasarkan karakteristik usia, paritas, kadar CA-125, IRK, gambaran histopatologi, stadium penyakit dan tindakan operasi di RSUP Haji Adam Malik tahun 2013-2016. Sampel penelitian adalah seluruh penderita kanker ovarium epitel yang tercatat di Departemen Obstetri dan Ginekologi RSUP Haji Adam Malik mulai selama periode Januari 2013 sampai dengan Desember 2016 yang berjumlah 42 orang.
Hasil penelitian menunjukkan bahwa pada umumnya sampel berumur antara 41-60 tahun yakni sebanyak 28 orang (66.7%) dan pada umumnya sampel adalah multipara yakni sebanyak 16 orang (38.1%). Mayoritas sampel memiliki kadar penanda tumor CA-125 lebih dari 35 yakni sebanyak 37 orang (88.1%) dengan RMI lebih dari 200 yakni sebanyak 32 orang (50.0%), menderita menderita adenokarsinoma serosa yakni sebanyak 24 orang (57.1%), memiliki stadium lanjut yakni sebanyak 22 orang (52.4%) dan pada umumnya sampel menjalani tindakan operasi Laparotomy Surgical Staging (LSS) yakni sebanyak 36 orang (85.7%). Kepada RSUP H. Adam Malik Medan disarankan untuk lebih meningkatkan kelengkapan data rekam medik khususnya tentang karsinoma ovarium epitel sehingga aspek-aspek yang diperlukan seperti data RMI, pemeriksaan kadar CA 125, histopatologi, stadium dan tindakan operasi memiliki data yang lebih akurat dan lengkap. | en_US |