| dc.description.abstract | Background And Objective :
Sepsis is the second highest death caused at intensive care unit and the 10 highest
death caused all over the world. According to Survival Sepsis Campaign 2012, the
early management for sepsis patients is 30 ml/kg crystalloid. In this study, we
compared the best type of crystalloid for resuscitation or EGDT for patients.
Method:
This study is a double blind randomized clinical trial, which starts from
December 2016-January 2017 at Haji Adam Malik General Hospital Medan. The
changes before and after fluid resuscitation of AGDA, electrolyte (Sodium,
Phosphate and Chloride) and lactate are observed on 40 potentially eligible
patients.
Result:
From 40 sepsis patients who undergo this study, the comparison of ringer acetate
malate and ringer lactate was observed. There is an improvement of AGDA result
on HCO3 ( p = 0,001), TCO2 ( p = 0,002) , BE (p = 0,048). While on electrolyte
results, there is a decreasing value for sodium ( p= 0,149). There is a better result
on lactate by administering ringer acetate malat ( p < 0,001). The administration
of ringer acetate malate gives higher value for AGDA, sodium and lactate
compared to ringer lactate.
Conclusion:.
The administration of ringer acetate malate on EGDT for sepsis patient is better
in maintaining acid-base equilibrium on the body compared to ringer lactate. | en_US |
