Hubungan antara Ultra Fitration Rate dengan Phase Angle yang Diukur dengan BIA pada Penyakit Ginjal Kronik dengan Hemodialisis Reguler

Abstract

Background: chronic kidney disease patients with regular hemodyalisis have high rates of morbidity md mortality that may be related to the hemod5mamic effects of rapid UFR and low PhA value. In this study, we investigated whether high UFR is associated with a Iow value of PhA thus indirectly affect the risk of morbidity and mortality as a whole. Aim: To investigate the relationship between UFR with PhA in CKD patients with regular HD and determine the optimal of UFR value in CKD patients with regular HD. Methods: A cross sectional observational study, began in May 2014, 92 CKD patients with regular HD (- 3 months) in the Hemodialysis Unit of IIAM Hospital Medan. UFR and BIA examination on subjects were recorded shortly after HD. Results: of the 92 study subjects, we obtained the number of HD regular CKD patients with PhA<4 based on the division of the UFR (cc/<g,4r) <10, 10-13, > 13, respectively are 3 people (15.8%o), 10 (52.6%). and 6 (31.6%), whereas patients with > 4 PhA based on UFR (cclkg,4r) <10, 10-13, > 13, respectively were 60 (82.2o/o), I 1 (15.1%), and 2 (2.7%) with a p value of 0.0001. The results showed that the optimal UFR in CKD patients with regular HD is <10 cc/kg/h. From the results of statistical analysis, we found a significant relationship between UFR with PhA (r= -0.536). After multivariate analysis, UFR and etiologic factors of CKD have a relationship that is still going strong with PhA (R =0.624, p = 0.0001). conclusion: In CKD patients with regular HD, UFR has inverse relationship with the value of PhA. After multivariate analysis, the UFR and the etiology of HD is still significantly affect the value of PhA. UFR optimal value in patients with CKD with regular HD is <10 cc/kg/h.