| dc.description.abstract | Fish farming is done intensively highly susceptible to outbreaks of diseas. The use
of antibiotics in the prevention of bacterial diseases can cause negative effects to
human health. Antibiotics can be replaced with the use of plant extracts containing
antibacterial compounds, one of which leaves frangipani (Plumiera rubra L.).
This study aims to determine the 96-hour LC50 value and safe concentration of
frangipani leaf extract of red tilapia fish seeds. The study is divided into two
stages, namely the preliminary test and the definitive test. Preliminary test was
conducted to determine threshold concentrations above and below the threshold,
where the concentration of the preliminary test is 0 ppm, 50 ppm, 100 ppm, 200
ppm, and 750 ppm. Definitive test using a concentration of 0 ppm; 98,40 ppm;
193,65 ppm; 381,10 ppm; and 750,00 ppm were obtained from calculations based
on the threshold concentration of 750 ppm and below the threshold of 50 ppm.
Percentage mortality of red tilapia in a preliminary test of the lowest to highest
concentration of 3,33%; 16,67%; 46,67%; and 76,67%. Percentage mortality
converted into the form used in the probit and probit analysis to obtain the 96-
hour LC50 value of 510,63 ppm. Safe concentration of 10% of the LC50 within
96 hours, which is 50,2 ppm. In the 96-hour LC50 valuesindicate that the leaf
extract of frangipani included in the category of moderate toxicity. | en_US |
