Perbandingan Hasil Kultur Apusan Orofaring pada Pasien Menggunakan Ventilator Sesudah 24 Jam yang Mendapat Dekontaminasi Oral Klorhexidine 0,2% dan Listerin di Unit Perawatan Intensif Rumah Sakit Haji Adam Malik Medan

Abstract

Objective : This research is aimed to observe comparison listerin and klorhexidine 0,2o/o as an oral decontamination drug to reduced oropharingeal bacteria. Method : Double-blind randomized clinical trial in 32 patients, aged above 18 years, Clinical Pulmonary lnfection Score (CPIS) smaller than 6, and used mechanical ventilator with oral intubation in intensif care unit Haji Adam Malik Hospital. The samples were divided into two groups, each composed of 16 people. One group were patients who receive Listerin 30 ml as decontamination oral every 12 hour for 24 hours. Another group were patients who receive Khlorhexidine 0,2% 30 ml as decontamination oral every 12 hour for 24 hours too. Oropharingeal swab was done altet 24 hours on lateral oropharyngeal mucosa near tonsil area with stetril stick swab, then specimen was sent to mikrobiology Laboratory to obatain antibiotik sensitivity and bacterial culture. ls recording result of bacterial culture and antibiotic sensitivity both of group. Reeult : ln the klorhexidine 0,2% group there were 3 patients (18,8%) were found positive baclerial growth and there were 1 1 patienls (68,80lo) positive culture oropharyngeal swab results from groups that use Listerine. The results of analysis using chi-square test shows that there are significant differences culture between patients were using Listerin and khlorhexidine 0,2o/o. From oropharyngeal swab culture results, patients that use Listerin would have 3,667 times risk bigger than khlorhexidine 0,2% with 95% lK (1,255-10,713). Conclueion : klorhexidine 0,2% is better than listerin as oral decontamination for inhibiting of oropharyngeal growth bacteria in first 24 hours.