Akurasi Pemeriksaan Sitologi Biopsi Aspirasi Jarum Halus pada Papillary Thyroid Carcinoma di Rumah Sakit Umum Pusat Haji Adam Malik Medan

Abstract

Background: Thyroid nodules are disorders of the thyroid gland, consisting of colloid nodules, cysts, thyroiditis found in about 80% of cases, while benign follicular neoplasms and thyroid carcinomas occur in about 10%-15% and 5% of cases, Papillary Thyroid Carcinoma (PTC). ) is an epithelial malignancy that shows follicular cell differentiation and has a number of specific nuclei. The most common thyroid carcinoma is PTC, with an incidence rate of about 80% of all thyroid carcinomas. Distinguishing preoperative benign lesions is very important to prevent unnecessary surgery, therefore fine needle aspiration cytologic biopsy (Si-BAJaH) is needed, easy to perform, accurate diagnosis and cheaper cost, so this examination is the first line in evaluating preoperative thyroid lesions. . Objective: Assess the accuracy of Si-BAJaH examination compared to histopathological examination in diagnosing PTC. Methods: This study is a diagnostic test study. The population of this study consisted of secondary data, namely patients with thyroid nodules diagnosed with PTC and non-PTC who underwent Si-BAJaH examination compared with histopathology at the Anatomic Pathology Unit of RSUP. H. Adam Malik, Medan. Results: Based on age group, from 62 samples, there were 56.5% PTC aged 41-60 years, (21.0%) 21-40 years, (19.4) and (3.2%) <21 years. There are 80.6% of the samples are female. PTC has a sensitivity value of 28.57%, specificity 100%, false positive 100%, false negative 73.21%, and accuracy 85.48%. This study can be used as a diagnostic tool for early diagnosis and a fairly accurate monitoring tool, however, a cytological diagnosis is not a substitute for a histopathological diagnosis which is still a definite diagnosis. A negative FNAB diagnosis is not necessarily a benign disorder, while PTC malignancies must continue with histopathology.