dc.description.abstract | Background : Bleeding from gastro-esophageal varices in cirrhotic patient is the
most serious and lite-threatening complication in every episode of bleeding. Approximately two
thirds of patients with decompensated cirrhosis and one third of those with compensated
cirrhosis have varices at the time of diagnosis. Endoscopic surveillance of esophageal varices in
cirrhotic patients is expensive and uncomfortable for the patients. Therefore, there is a particular
need for noninvasive predictors for esophageal varises.
, Objective : The aim of the present study was to evaluate association of
esophageal varices and Form index as noninvasive parameter in liver cirrhosis patients.
Methods : This is a cross-sectional study of patients admitted at the Adam
1v1alik hospital Jviedan between September to December 2014 with a diagnosis of cirrhosis based
on clinical, biochemical, ultrasound, and gastroscopy. Foms index vvas calculated for all patients,
tabulated and analyzed.
Results Among 51 patients with esophageal varices, 58,8% was due to HBV.
The majority of patients were Child C \Vith only 13,2% being Child Pugh class A lvfajority of
the population had F2 esophageal varices (37,3~0
'o), F3 (33,3), and Fl (29,4%). There is
significance difference between Foms inclcx and grading of esophageal varices, Forns index is
_higher in large esophageal varices compared -.vith small esophageal varises (8,47 ± 2,05 vs 6,37
± 2,68; p = 0,001). Foms index cut-off value of >7,92 was highly predictive in the diagnosis
large esophageal varices \Vith a sensitivity of 63,9%, specificity of 73,3%, positive predictive
value of 85,2%, negative predictive value 45Js~o, and accuracy was 71,71
}'0
Conclusion : Forns index ,vas significantly associated with esophageal ,,rarices.
Forns index is a good noninvasive predictor of esophageal varices in cirrhotic patients. | en_US |