| dc.description.abstract | Chives ( Allium schoenoprasum L. ) is a long-lived plants which are very
easy to grow . This plant is known as the vegetable of the Liliaceae family . All
parts of the chives edible . Chives can also be used fresh or boiled as part of spice
in cooking . Chives leaves contained a variety of phytochemical compounds
included alkaloids, flavonoids, glycosides, steroids, tannins and various minerals
such as potassium, magnesium and sodium. The most highest contain was
potassium which is believed to dissolve calcium oxalate in kidney stones.
The aims of this study was to determine the solubility of calcium oxalate by in vitro and in
The in vitro method was dissolving calcium oxalate in a variety of chives
leaves infuse which was incubated at 37oC for 4 hours, while the in vivo method
was using animal model and induced by 0.75% ethylene glycol and 2%
ammonium chloride. The animal model divided into 6 groups : Normal group,
negative control, positive control, Pl (LDKS), P2 (LDKK) and P3 (LDKD).
Groups of Pl, P2 and P3 added by a variety of chives leaves infuse. The
parameters investigated are the kidney shape, kidney colour, ratio of kidney
weight, and the histopathological of kidney tissue, The minerals content was
measurement using atomic absorption spectrophotometty.
Results of in vitro studies showed that all variety of chives leaves infuse
can dissolve calcium oxalate which the highest solubility was using the dried
chives leaves infuse, which can be seen from the level of dissolved calcium at
56.796 g/ml. with 5.68 % solubility percentage.
While the data of in vivo studies showed that P2 (LDKK) group was the
most effective in dissolve the kidney stone and able to reduce the kidney weight
ratio. The conclusion of this study was chives leaves infuse proved on dissolving
the kidney stone calcium compounds both of in vitro or in vivo. These studies
prove that the infusion of chive leaves can be the alternative to kidney stone prevention. | en_US |
