Rasio Platelet-Limfosit sebagai Prediktor Kejadian Kardiovaskular Mayor dalam 6 Bulan pada Pasien dengan Infark Miokard Akut ST Segmen Elevasi di Rumah Sakit Haji Adam Malik Medan

Abstract

Coronary atherosclerotic disease is the leading cause of mortality and morbidity in both established and developing countries. Acute coronary syndrome (ACS) in form of acute ST segment elevation myocardial infarction (STEMI) is one of the manifestations that associated with high mortality rate in the first 30 days. Nowadays, the usefulness of platelet-lymphocyte ratio (PLR) has been studied as predictor of death in STEMI patients. The aim of this study is to assess the usefulness of PLR as a long term predictor against major cardiovascular events (MACE) after 6 months from first onset of STEMI This in a retrospective study that enrolled 100 patients that diagnosed with STEMI. Secondary data were obtained from RSFIAM medical record and the value of PLR was calculated using the first laboratory result when patients were admitted to the CVCU ward. Patients were categorized as low PLR group (s144) and high PLR group (>144). Follow-up were done in all patients for 6 months and death, heart failure, arrhythmia and reinfarction were counted as MACE. From data analysis, we found 53 patients (53%) having MACE and among that we found 33 patients (62,3yo) is in high PLR group. We also found significant correlations between high PLR and death (p: 0,010; OR: 3,778;95o/o CI:1,461- 9,767), high PLR and reinfarction(p: 0,031; OR: 1,081;95Yo CI:0,990-1,181), and high PLR and total MACE (p <0,001; OR: 9,429;95%oCI:3,552-25,03). We can conclude that PLR is a useful long term independent predictor againstMACE, particularlydeath and reinfarction in STEMI patiens