Hubungan Profil Hematologi dengan Mortalitas dan Lama Rawat Pasien Covid-19 Derajat Berat di RSUD Dr. Pirngadi Medan Tahun 2021

Abstract

Introduction. November 2020, WHO reported that there had been around 60 million cases of COVID-19 worldwide th at is caused by SARS-CoV-2 and 1.5 million of them had died. Hematological examination in COVID-19 patients shows abnormal conditions and some laboratory tests can predict the prognosis. Purpose. analyzed relationship of hematological profile (hemoglobin, leukocytes, platelets, neutrophils, lymphocytes, NLR, D-dimers) with mortality and length of stay in severe COVID-19 patients in RSUD. Dr. Pirngadi Medan in 2021. Method. This research is an analytic descriptive research with cross sectional design. 55 people of this sample selected by the method of consecutive sampling. Data collection from medical records and analyzed by SPSS, both from univariate and bivariate (Mann-Whitney test). Results. Hematological profile of patients was anemia=60%; leukositosis=58,2%; neutrofilia=70,9%; limfositopenia=54,5%; NLR ≥ 3,3=87,3%; trombosit normal=74,5%; increase in D-dimer=90,5%. The results showed sig = 0.201; 0.034; 0.017; 0.021; 0.040; 0.021; 0.019; 0.044 for the relationship of hemoglobin, leukocytes, neutrophils, lymphocytes, NLR, platelets, D-dimers, and comorbid with mortality. The analysis showed sig = 0,571; 0,110; 0,509; 0,219; 0,881; 0,198; 0,254; 0,326 for the relationship of hemoglobin, leukocytes, neutrophils, lymphocytes, NLR, platelets, D-dimers, and comorbid with length of stay. Conclusion. Hematological profiles that are often encountered are Anemia, leukocytosis, neutrophilia, lymphocytopenia, NLR ≥ 3,3, normal platelets, and increased D-dimer. There’s a relationship between leukocyte, neutrophil, lymphocyte, NLR, platelet, and D-dimer levels with mortality, while hemoglobin has no relationship. There was no relationship between hematology profile with length of stay.