Faktor-Faktor yang Memengaruhi Luaran Pasien Covid-19 dengan Diabetes Melitus Tipe 2 di Rumah Sakit Haji Adam Malik Medan

Abstract

Background. COVID-19 is a highly contagious viral infection by SARS-CoV-2 which caused worldwide pandemic and high mortality. One of the many risk factors for worse clinical outcomes in COVID-19 patients is the presence of comorbidity. Diabetes Mellitus is a chronic metabolic disease often found in COVID-19 patients. The insulin resistance that led to chronic inflammation on the body may worsen the clinical outcomse on COVID-19 patients. Objectives To examine the factors affecting clinical outcomes on COVID-19 patients with T2DM. Methods. The method used an analytical method with cross sectional design. Population is inpatients in Haji Adam Malik Hospital diagnosed with COVID-19 and Diabetes Mellitus Type 2 with 99 inpatients as sample. The data used are secondary data obtained through medical records from a hospital covering patients characteristics and laboratory result such as blood glucose level, HbA1c, CRP, D-dimer, Ferritin and total cholesterol. The data was analyzed using t-independent and chi square test with SPSS program. Result. Clinical outcomes for 99 patients are 60 patients are cured and 39 patients are dead. Analytical study found there is a significant correlation between factors affecting clinical outcomes on COVID-19 patients with T2DM that are HbA1c level, D-dimer, cholesterol total and COVID-19 degree of severity and the clinical outcomes (p<0,05). Conclusion. Based on the result, HbA1c level, D-dimer, total cholesterol and the infection degree of severity affects the clinical outcomes on COVID-19 with T2DM inpatients in HAM Hospital (p<0,05).