Gambaran Peningkatan Kadar Gula Darah pada Penderita Diabetes Melitus Tipe 2 terhadap Progresivitas Penyakit Covid-19 di Rumah Sakit Umum Pusat Haji Adam Malik Medan

Abstract

Background: COVID-19 is the result of infection with the SARS-CoV-2 virus which has many cases of death with a certain level of severity. The varying severity of COVID-19 clinical symptoms is related to certaid comorbid conditions such as the presence of disease such as cardiovascular disease, hypertension, coagulation disorders, and diabetes melitus. Diabetes Melitus is considered one of the worst risk factors for COVID- 19 and is associated with poor prognosis for Diabetes patients. Objectives: To see an overview and correlation of the increase in blood glucose level in patients with Diabetes Mellitus type 2 on the clinical outcomes of COVID-19 disease in patients at H. Adam Malik Medan Hospital, Methods: This research is an analytics study using cross sectional design. Data were taken from samples in the form of medical records from COVID-19 patients with comorbid type 2 Diabetes Mellitus from January 2022 – October 2022 using a consecutive sampling technique. Results: The prevalence of COVID-19 with type 2 Diabetes Mellitus in patients at H. Adam Malik Medan Hospital in January 2022 – October 2022 was 15,5%. Uncontrolled HbA1c as much as 78,6%. Uncontrolled fasting blood glucose level as much as 92,9%. 2 hours post prandial blood glucose level uncontrolled as much as 78,6%. Moderate covid-19 severity is 45,7%, severe is 35,7%, and critical is 18,6%. Patient mortality as much as 45,7%. The results of statistical test calculations using the spearman correlation test showed that there was a significant correlation between uncontrolled HbA1c and the patients severity of infection (p=0,038), there was no correlation beetween fasting blood glucose level and patients severity of infection(p=0,244), there was a significant correlation between 2 hour post prandial blood glucose level with patients severity of infection(p=0,048). Conclusion: There is a significant correlation between HbA1c and 2 hour post prandial blood glucose with the severity of COVID-19 infection. There is no significant correlation between uncontrolled fasting blood glucose level with the severity of COVID-19.