Perbedaan Derajat Anemia pada Pasien Penyakit Ginjal Kronik yang Mendapat Hemodialisis dan Non-Hemodialisis

Abstract

Background. Chronic kidney disease (CKD) is an abnormal function and structure of the kidney that lasts more than 3 months and develops slowly and progressively. Management of chronic kidney disease is carried out with two therapies, those are conservative therapy (non-hemodialysis) and kidney replacement therapy, namely dialysis (hemodialysis and peritoneal dialysis), and kidney transplantation. Chronic kidney disease affects the production of erythropoietin which has an impact on the occurrence of anemia where anemia occurs in 80-90% of patients with chronic kidney disease, especially in stage 3 CKD and is almost always found in CKD stage 5. Objective. Comparing the degree of anemia in CKD patients receiving hemodialysis and non-hemodialysis.. Methode. The research conducted was an analytic study with a cross sectional design. Data were obtained secondary from the medical records of CKD patients at HAM Hospital and USU Hospital in 2021 with a total sample of 134 patients. Results. In this study, the most gender was male (65.7%), the most age group was the late elderly (34.3%), the highest CKD degree was at stage 5 (50%), the highest creatinine level was found in CKD stage 5 namely 9.89 mg/dl, the highest degree of anemia was moderate anemia (50% ) where the majority were found in the late age group (40.3%) and stage 5 CKD (44.8%), then CKD on hemodialysis had more severe degrees of anemia. Analysis of research data using the Mann- Whitney test method was obtained p = 0,00 which showed that there are differences in the degree of anemia in CKD patients who receive hemodialysis and non-hemodialysis.. Conclusion. There are differences in the degree of anemia in patients with chronic kidney disease who receive hemodialysis and non- hemodialysis.