| dc.description.abstract | Antimicrobial Resistance (AMR) is the ability of microbes to inhibit the effects of
treatment to fight infection. If inappropriate use of antibiotics continues and is not
controlled, it will threaten livestock in Indonesia. To find an overview and risk factors
regarding AMR, AMR testing was carried out on E. coli isolated from broiler farms in
Medan and Deliserdang Regency. A total 41 of E. coli were isolated from cecum specimens
taken from poultry slaughterhouse and were representatives of broiler farm. The sample
was then tested for sensitivity to antibiotics using the Microbroth Dilution technique
(Sensititre® Microplate) with the CLSI VET01S (2015) and CLSI M100 (2018) standards.
Information on risk factors was taken from farms using a questionnaire and analyzed using
a logistic regression model (EPI Info 7 CDC).
The samples were tested for sensitivity to 13 types of antibiotics and showed
Trimethoprim had the highest sensitivity level (95.1%) followed by Ampicillin (90.2%),
Gentamicin (87.8%), Nalidixide acide (85.4%), Cefotaxim (82.9%), and Sulfamethoxazole
(82.9%), while the antibiotics Colistin and Meropenem have not shown resistance. A total
of 92.7% of E coli had experienced Multi Drug Resistance (MDR). Analysis of the
questionnaire identified that farmer knowledge about AMR had a very strong influence on
the incidence of MDR in E coli with a 23 times probability than farmers who did not know
about the incidence of AMR in broiler farms. The AMR incident requires the coordination
of the relevant agencies to carry out socialization and assistance to farmers in providing
correct knowledge and using antibiotic wisely. | en_US |
