Korelasi Tingkat Gejala Depresi dengan Kadar Interleukin-6 pada Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis Reguler

Abstract

Depression is common in patients with chronic kidney disease (CKD) that requiring hemodialysis (HD), and with additional morbidity and mortality. This is associated with chronic inflammation suffered by patients, that characterized by elevated levels of plasma cytokines, especially interleukin (IL-6). There for, IL-6 has an important role in coordinating the underlying biological pathways of depression