| dc.description.abstract | Liver cirrhosis is advanced stage of chronic hepatic disease and This
condition can lead to multiple complications due to portal hypertension. At the
time of diagnosis of liver cirrhosis approximately 600/o of patients with liver
cirrhosis have undergone varying degrees of esophageal varices.
The aim of this study was to asses the correlation of Simpler Score with
esophageal Varices in patient with liver cirrhosis
A cross sectional study had been done in 76 cirrhosis patients consists of
57 males and 19 females who underwent treatment in the inpatient unit and
policlinic of Gastroenterohepatology division at H. Adam Malik hospital from
September 2014 until January 2015. Anamneses , physical examination and
laboratory examination were done. Univariate and bivariate analysis (
Independent t test and chi square test ) were done using SPSS version 17
There were significant differences between mean of Simpler score in small
esophageal varices and mean of Simpler Score in large esophageal varices
(p:0,000). In addition there were significant differences between mean value of
platelet, total bilirubin, AST, Albumin, PT, INR, Gamma GT, ALT in small
esophageal varices and large esophageal varices (p<0.05). There were no
significant differences between mean of age in patient with small esophageal
varices and large esophageal varices ( p>0.05).
There were significant association between severity of liver cirrhosis,
severity of ascites with size of esophageal varices (p<0.05).
simpler Score with the cut - off) 0.9558 can identify existing large
esophageal varices endoscopically while the value of the cut - off< 0.9558 able to
identify the presence of small esophageal varices endoscopically. Predictive value
of Simpler score with cut - off > 0.9558 in diagnosing large esophageal varices
with sensitivity 80.4o2, specificity 80%, PPV g9.13%, NPV 66.6i/o, and has
AUROC 0.876.
In conclusion Simpler Score accurate in predicting the size of esophageal
varices particularly large varices in patients with liver cirrhosis, so it may be an
alternative option of non - invasive method to detect the presence of large
esophageal varices | en_US |
